Uphando lwe-Alzheimer's disease luye lwabangela ezinye iingqondo ezintle kwiingcali zonyango kwixesha elidlulileyo le-20. Nangona abaphandi bafunde ezininzi ngezifo, ukugula kwayo, kunye neziphumo zayo, inkqubela phambili encinci eyenziwe ekulwa nesifo.

Iqela emva kweziyobisi zezilingo J147 (1146963-51-0) wanquma ukuthatha indlela eyahlukileyo. Iziphumo zakuqala ziye zazimangalisa, kwaye abaphandi baqhubeka befunda ukuba le nkunkuma entsha inxibelelana njani neeseli ezahlukeneyo zomzimba.

 


 

Yintoni i J147?

 

I-J147 yi-nootropics powder yokuqala eyenziwa kwi-2011. Abaphandi baye bafumanisa ukuba izidakamizwa, kwiinkalo ezahlukeneyo ezahlukeneyo, zinokuphelisa ukulahlekelwa kweememori kunye nokukhawuleza, nokuba zibuyele, i-Alzheimer kwimigundane.

I-J147 powder yi-pheny hydrazide. Itholakala kwi-curry ye-spice ye-curry. Kuyinto enobungozi obuphantsi. Nangona kukho ukukhathazeka kwangaphambili, i-J147 powder ayizange iboniswe ngokuba yi-carcinogenic. Abaphengululi bavavanyelwe ngokubanzi ngoku kuhlola i-metabolites ye-J147 kwimicrosomes yabantu kunye ne mouse kunye neplasma yemouse.

Iziphumo zibonise ukuba i-J147 ayinakulinganiswa ne-amines enamakha okanye i-hydrazines.

 


 

Iindlela eziqhelekileyo zokulwa ne-Alzheimer's

 

Uninzi lweziyobisi eziphuhlisiwe kwixesha elidlulileyo le-20 lijoliswe kwi-plaque yamayloid egcinwe kwiibilini zezigulane ze-Alzheimer. Le ndlela yenza ingqiqo yokuba ezo zidiphozi ziyakhupha iiseli zesisongela ukuba zife.

Nangona kunjalo, emva kweminyaka eyi-20 ayikho nayiphi inkqubela phambili kwiimvavanyo zeklinikhi kunye nawaphi na amachiza ajolise kwiplates.

Indlela ehambelana nayo ihlose ukuzama ukujolisa i-amyloid ngaphambi kokuba ifake i-deposit deposits. I-amyloid ibhubhisa i-synapses ngaphambi kokuba ifakwe kwi-plaque clumps. Nangona kunjalo, nangona okujoliswe kwangaphambili akubonakali ukuba kusebenza.

Kuze kuphuhliswe i-J147 (1146963-51-0), unyango lwama-Alzheimer lwalusesikhundleni. Kwakungekho naluphi na umkhondo ocacileyo kunye naliphi leziyobisi eziye zaphuhliswa kwiminyaka eyi-20 eyadlulayo kwaye ukukhubazeka kwesi sifo ngokwawo akuzange kubolekise nakwezinye iindlela ezibonakalayo.

 


 

Indlela i-J147 (1146963-51-0) isebenza ngayo ne-Alzheimer's

 

Iqela emva kweJ147 linqwenela ukuthatha ingqiqo eyahlukileyo ekulweni ne-Alzheimer's. Esikhundleni sokuphuhlisa esinye isidakamizwa esicwangcisa i-amyloid, iqela lagqiba kugxininisa ingozi enkulu ye-Alzheimer's. Into ebaluleke kakhulu yengozi yokuguga-ngoko iqela lijika imizamo yalo ekukhuseleni ukuguga.

Iqela lenze i-J147 ngokusebenzisa izikrini ezisekelwe kwiseli ezinobungozi obudala beengqondo. Ukusuka kwezi zikrini, baqulunqa i powder J147.

I powder J147 isebenza ngokunciphisa umsebenzi we-ATP synthase kwi-mitochondria. Ezi iisensi ze-neuronal ezivela kwiindawo ezininzi ezinobungozi bobuchopho obudala. Uphando lubonise isizathu sokuba le ngqungquthela ivelise le mphulo ye-neuroprotective ngenxa yendima ye-excitotoxicity inomonakalo we-cell neuronal.

I-neurons yonakaliswe kwaye ibulawe ngokugqithiswa kwama-receptors kwi-glutamate ye-neurotransmitter ye-excitatory. I-J147 iyanciphisa iinkqubo ezithile ezinobungozi obudala beengqondo. Oku kugcina i-neurons kwaye, ngokubhekisele ngakumbi, kunokubangela ukuguqulwa kweminye yemiphumo echazwe ngakumbi ye-Alzheimer's.

 


 

ImiSebenzi ye-J147 njenge-Agent Aging Aging

 

I-mechanics ye-J147 ayifani nezinye iziyobisi ze-Alzheimer eziye zafikelela kwisigaba esifanayo sophando. Ngenxa yokuba ingagxininisi kwi-pathology yendabuko yesifo, kodwa kunokuba isebenze ukunciphisa ingozi eyenziwa ngumguga wokuguga.

I-J147 isebenza njenge-agent anti-aging agent. Ngasekhohlo ukuya kumacebo alo, ubuchopho bomntu buhlakulela ezithile ezinetyhefu. Zizo zonyango ezinxulumene nobudala obudala indawo yokuLungisa i-Alzheimer. I-J147 ijika iwashi kulezi zityhefu, kwaye oku kwenza kube nzima kwi-Alzheimer ukuba yenze umsebenzi wayo wokuhlahloka kwemimori ehlukeneyo yememori.

Kungenokwenzeka ukuba indlela yokuphayona nguJ147 iya kuba luncedo ngaphezu kokuphela kokulwa no-Alzheimer's. Ama-anti-anti aging agents angakwazi ukujolisa kwezinye izinto ezinobungozi obangela ezinye izifo kunye nezifo apho ubudala bodwa buyingxaki ebalulekileyo yengozi. I-J147 ayikho nje isiyobisi se-Alzheimer. Ngokwenene isiyilisi esinceda ukuguqula ukuguga ngokwayo.

 


 

J147 Uvavanyo lweZliniki

 

Nangona i-J147 yaqala ukuphuhliswa kwi-2011, ngoku ifikelele ukuvunyelwa kwezilingo zamachiza. Kwizithuba zonke endleleni, i-J147 iboniswe kungekhona nje ukuba iphumelele ngokukhawuleza, kodwa iboniswe ukuba izinzile.

Ukukhathazeka kwangethuba malunga nokuba kungenzeka ukuba i-J147 ibe yi-carcinogenic, okanye enye inetyhefu, iboniswe ingenasiseko.

Abaphandi banomdla wokufumana izilingo zeklinikhi kwaye phantse wonke umntu ochaphazelekayo uphando lwe-Alzheimer unethemba lokuba i-J147 iya kubonakala iyasebenza kubantu njengokuba ikwasegundwini nakwii-laboratory.

 


 

Iziphumo zokuqala zeJ147

 

Ekuqaleni kwabaphandi bafumanisa ukuba iJ147 (1146963-51-0) unokuthintela, kwaye uguquke, ukulahlekelwa kwememori kwiimiceba ezine-alzheimer. Nangona kunjalo, njengethemba njengaloo nto, kwaba bantu, kuphela malunga ne-1% yezigulane ze-Alzheimer zinelifa elizuze ilifa. Ifomu eqhelekileyo ye-Alzheimer ayinxulumene nesethi ethile yemfuza, kodwa ngokuguga ngokwayo.

Iqela kunokuba lifunde iziphumo zeJ147 kwiqela leegundana ezisekudala kwaye zifumana uhlobo lomqondo ochaphazelekayo ofana ne-Alzheimer enobudlelwane obudala obufumaneka kubantu.

Iziphumo zolu cwaningo lwesibini nazo zithembisa. I-J147 yakwazi ukuhlangula ukulahlekelwa kwengqondo, nangona ilawulwa kwimiqathango yokugqibela yesifo. Iphucule imemori kwiimiceba kwaye ikhusele ukutshabalalisa okunye.

Kwakhona kwafumanisa ukuba xa i-J147 idibaniswe ne-fakepezil isebenze kangcono ukubuyisela imemori yesikhokelo kunye nekerubhi. Kodwa, i-J147 yedwa ephezulu ekubuyiseni imemori yendawo.

 


 

Ixesha elizayo I-J147 (1146963-51-0)

 

Kukho indlela ende ngaphambi kokuba iJ147 (1146963-51-0) ifumaneke ukuphatha izigulane ezininzi ze-Alzheimer. Okokuqala isilwanyana kufuneka sigqibe isigaba esilungileyo sesilingo. Emva kokuba iimvavanyo zeklinikhi ziye zahlaziywa ngoontanga, inkqubo yokuvunyelwa kwe-FDA iza kuqala.

Abaphandi baqwalasela isidingo esiphuthumayo sokwenza unyango olunefuthe kwi-Alzheimer's disease, kodwa bayazibophezela ukuba bangagxininisi isayensi. Kuze kube ngoku, zonke iziphumo ze-J147 zichaneke kakhulu kwaye akukho nanye isilwanyana se-Alzheimer esake sajonga oku kulungele kule nkqubo.

 


 

Okunye malunga neJ147:

I-Raw Tadalafil (Cialis) powder hplc≥99.5% | Yenza i-tadalafil powderfil

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I-Tadalafil ipowder for sale: Indlela yokukhetha umthengisi we-tadalafil?

 

Ukuxilongwa kweMvavanyo ye-J147 yokuguga kwe-Alzheimer | AASraw

 


 

 

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