Isikhokelo sokuthenga esigqibeleleyo se-SARM SR9009 sokwakha umzimba
I-AASraw ivelisa i-Cannabidiol (CBD) ipowder kunye ne-Hemp ebalulekileyo yeoyile ngobuninzi!

 

Isikhokelo sokuThenga ngokugqibeleleyo se-2019 se-SR9009 sokwakha izihlunu ezingaphezulu

 

1.Yintoni SR9009?

SR9009 okanye i-stenabolic sisongezelelo se-CAS 1379686-29-9 esilingisa iziphumo zokuzilolonga kwe-cardio. Ayisiyi kukunceda kuphela ekunciphiseni amanye amafutha omzimba wakho, kodwa iya kukonyusa amandla akho ngelixa ukonyusa unyamezelo.

I-SR9009 sisiciko esenziwe ngezinto zokwenziwa, esivele sabakho ngenxa yeengcali zikaNjingalwazi uThomas Burris. Inxulumene ngokusondeleyo ne SARMS (I-Androgen Receptor Modulators ezikhethiweyo), kodwa ilusizi ku-Rev-Erbcy iprotheni efumaneka kwimithambo yethambo, izicubu ze-adipose, ubuchopho kunye nesibindi.

Uprofesa Burris weza SR9009 (I-1379686-29-9), inenjongo yokufunda nokuqonda isigqi esijikelezayo.

 

I-2.Isebenza njani i-SR9009?

Ngaba uyazi ukuba le mvakalelo uyifumanayo emva kokuqhuba i-2km kwi-treadmill okanye ukuphakamisa ezinye i-hardweights? Ewe, i-SR9009 isisindo sokulahlekelwa kwesisindo iya kukwenza uzive ngendlela efanayo. Isongezelelo sinendima ekuguqulweni kwe-circadian, umgaqo we-lipid, kunye nokulawulwa kwamanqanaba eglucose.

I-SR9009 SARM idlala indima ebalulekileyo ekuvuseleleni iRev-Erb. Le proteni ichaphazela ukubanakho komzimba ukutshisa amanqatha amaninzi, iswekile, kunye ne-cholesterol embi. Ke ngoko, inyusa inkqubo yokunciphisa umzimba ngelixa iphucula unyamezelo. Nokuba ubuzilolonga, uya kuziva unamandla kwaye awudinwanga kangako ukuze ukwazi ukwenza uqeqesho ngakumbi lomzimba.

I-Stenabolic yenza amanqatha, ii-lipids kunye neeswekile. Xa umbane usetyenziswa ngokugqibeleleyo, ngokuqinisekileyo uya kufumana ukusebenza okuphezulu. Kwisifundo saphambi kokusebenzisa iimodeli zemigca, iimpuku ezaziphantsi kwe- I-SR9009 powder (I-1379686-30-2) umthamo wawunakho ukuqhuba kabini ngokukhawuleza kunangaphambili. Esi siqwenga sobungqina sinokuba sisizathu sokuba i-stenabolic idweliswe phakathi kweziyobisi ezingavumelekanga kwimidlalo.

Ukuba awuyiyo i-maniac yokuzivocavoca, ezi ndaba zezi iindlebe zakho zifuna ukuva. I-Stenabolic iphinda iphindwe kabini inqanaba lokunciphisa umzimba xa uphumla. Emva kokutya, umzimba wakho uguqula ukutya kube ngamanqatha. Nangona kunjalo, i-SR9009 yokuncipha kokunciphisa umzimba kuya kuyomeleza kwangoko imetabolism yokuba uza kuqala ukutshisa la mafutha kwangoko.

Izifundo zamva nje zibonisa ukuba i-stenabolic ngummeli olwa nomhlaza. Umchasi womhlaza we-SR9009 ochaphazela abaqhubi be-oncogenic, kubandakanya i-PIK3CA, HRAS, kunye ne-BRAF. Kwiiseli ezingalunganga, imveliso inchukumisa i-apoptosis kunye nokukhubazeka kwesisu ngaphandle kokudala iziphumo ezibi.

 

Isikhokelo sokuThenga ngokugqibeleleyo se-2019 se-SR9009 sokwakha izihlunu ezingaphezulu

 

I-3.Indlela yokusebenzisa i-SR9009

Ngaphandle kwelebheli esetyenzisiweyo ye-SR9009 inzuzo yemisipha ichiza, isongezelelo sinemilinganiselo ebalulekileyo yamayeza. Ooklinikhi bancomela kakhulu kubaguli abanesifo seswekile kunye nabo bantu basengozini yokubetha.

Ukuba ucwangcisa ukulawula i-SR9009 powder (1379686-30-2) ngokulawula ukugula kwakho, qiniseka ukuba uthethe nogqirha wakho kwangaphambi kokuba ubenako. Eli chiza likhuselekile, kodwa ugqirha wakho kufuneka akucebise malunga namayeza ngoku ngelixa ujonga naziphi na iimpawu ezibi.

Ukusetyenziswa kwelebheli engekhoyo, idosi eyiqhelekileyo ye-SR9009 imalunga ne-30mg / ngosuku. Idosi yahlulahlulwa kathathu.

Ukuba emva konyamezelo, kuya kufuneka uthathe isongezo ixesha elifutshane ngaphambi kokubetha umthambo. Isizathu kukuba i-SR9009 ine-half-life; ngenxa yoko, iziphumo zibonakalisa kwifleshi. Ngokufanelekileyo, yiphathe ngaphambi kwesidlo ukuze ukwazi ukugcina imetabolism efanelekileyo imini yonke.

 

I-4.Iimpawu zeSR9009, Ucinga ntoni?

  • Nyusa ukuthoba umzimba

I-SR9009 SARM iphucula iinkqubo ze-metabolic. Nje ukuba ukungenisa kwenzeke, i-stenabolic iya kuthi icwangcise umzimba ukuba utshise ii-calories ezingaphezulu kokuziguqula zibe ngamafutha. Isongezelelo asipheleli nje ekulinganiseni ugcino lwamafutha, kodwa sinciphisa ukuveliswa kweeseli ezitsha zesibindi esibindini.

Ukuba injongo yakho kukulahlekelwa ngumzimba, qiniseka ukuba ubandakanya imisebenzi yomzimba kwindlela yakho. Ukusebenza ngaphandle, ukutya, kunye nokuthatha i-SR9009 pre yokusebenzela yokunyusa ukukhawulezisa ukutshiswa kwamafutha athe kratya. Uphando lubonisa ukuba ukusebenzisa i-stenabolic kunciphisa amanqatha kunye ne-plasma triglycerides concentration yi-23% kunye ne-12%, ngokulandelanayo.

Kwiimeko ezimanyumnyezi apho ukusebenza okanye ukutya kungasendawo inketho, oogqirha banokukubonelela oku kongezwa.

Ukutshekisha kuhlolo lwabathengi, omnye umsebenzisi uqinisekise ukuba i-SR9009 powder (1379686-30-2) wamnceda ukuba alahle i-17 yeepawundi kwiinyanga ezintathu.

  • Ukukhula koMzimba

Esi songezelelo asonyusi kuphela ubunzima bemisipha kodwa siphucula amandla kunye nokusebenza. Imvakalelo oyifumana emva kokuhambisa idosi ye-SR9009 ilingana naleyo yokuphakamisa ubunzima.

Iyeza livuselela ukuveliswa okukhulu kwe-mitochondria ngaphakathi kweeseli zemisipha, ngenxa yoko ukuphakama kwemetabolism. Ezi organelles zinoxanduva lokuvelisa amandla kwizicubu zemisipha. Ngaphandle koko, kuya kubakho ukwanda kokusetyenziswa kweglucose kunye nokutya okunamafutha ngaphakathi kwezihlunu.

Ngokwonyango, i-SR9009 izisa uncedo kubantu abadala abanengxaki yokuhla kwemisipha okanye i-sarcopenia.

  • Ukwandisa Ukunyamezela

Uninzi lwabantu abenza umthambo abayi kuphoswa kukubandakanya izihlunu ze-SR9009 ezifumana iziyobisi kwirejimeni yazo yokwakha umzimba. Uya kuphakamisa iintsimbi, usebenze umatshini wokunyathela, okanye wenze nawuphi na umthambo ngaphandle kokuziva udiniwe okanye unentloko elula.

Isongezelelo ngokungathandabuzekiyo siyakuthatha intsebenzo yakho njengenotshi ephezulu kunangaphambili. Ukuba ucinga ukuba ezi zibonelelo ze-SR9009 bubuqhetseba, kuya kufuneka ubuze ukuba kutheni i-arhente echasene nokusetyenziswa kweziyobisi inokukuthintela ngokuqinileyo ukusetyenziswa kwayo kwimidlalo yokhuphiswano.

Njengoko uThomas Burris, umsunguli we-Stenabolic, etshilo, ichiza liyakuguqula ube yimbaleki enamava ngexesha elithile. Awuyi kuphelelwa ngamandla okanye amandla nokuba wenza imithambo enzima.

  • Yongeza ukuPhaphama

Ukuba uhlala unxilile ngexesha losuku, i-stenabolic inokuba lilo iyeza lakho. Kwisifundo sangaphambi kokugqibela, isongezelelo sabonakala ngathi siyiguqula indlela yokulala yeemodeli zokuphamba. Izazinzulu zaphawula ukuba ezi mbeba zaziphapheme ngakumbi ngexesha lasemini, kwaye akukho namnye kubo owayenokulala ubuthongo obunzulu. Ke, ukuba ufuna ukukhaba ungene kwisigqi sakho se-circadian ukuguqula iphethini yakho yokulala, i-SR9009 iya kuyenza ngovuyo.

Enkosi kwi-SR9009 emfutshane yobomi obunesiqingatha, isiphumo sokuvuka sinokuhlala ixesha elifutshane. Ke ngoko, awuyi kulala imini yonke.

  • Ukonakaliswa kweTishu (Fibrosis)

Uphando luqinisekisa ukuba iigundane ezinesibindi fibrosis zabuya kwakhona emva kokuthatha i-SR9009 kwiiveki ezimbini.

  • Ukukhusela kwisifo seNhliziyo

Kwimeko apho intliziyo ikhula ngendlela engaqhelekanga, i-SR9009 powder (1379686-30-2) isebenza ukubuyisela umva i-anomaly ngokunciphisa ubungakanani bezitho kunye nobunzima. Xa ezinye iimpuku zemithambo-luvo elukhuni zanyangwa nge-stenabolic, abaphandi baqaphela ukuncitshiswa kwesilonda semithambo yegazi emva kweeveki ezisixhenxe.

Abanye abasebenzisi bayazi ukuba isongezelelo sidlale indima ephambili ekucutheni uxinzelelo lwegazi labo.

  • Iyancipha iCholesterol yegazi

Ukuba utyebile, amathuba okuba amanqanaba akho e-cholesterol aphezulu. I-SR9009 iya kunciphisa iye kuthi ga kwi-47% ye-LDL, ngaloo ndlela yenza ukuba ukusebenzisa kwakho kube nemveliso ngakumbi. Kuya kufuneka uqaphele ukuba isongezelelo asichaphazeli amanqanaba e-HDL.

  • Ukuthoba ukuvuvukala

I-Rev-Erbs idlala indima ebalulekileyo ekulawuleni ukuvuvukala kunye nokulimala ngaphakathi kwe-CNS. I-SR9009 ivuselela ii-receptors zenyukliya ze-Rev-Erbcy, ezinemiphumo yokuthintela ukosuleleka.

Isiyobisi siyacinezela ukuveliswa kwee molekyuli ezinokutsha ezinje nge CCL2, MMP-9, kunye ne TNF-α. Njengoko ukulimala kwezicubu kunye nokuvuvukala okungapheliyo kuyimpawu ze-oncogenic, izazinzulu zifunda ngethemba lomdlavuza wesifo somhlaza kwi-SR9009 kwi-oncogene-indened senescence.

  • Unciphise ixhala

I-SR9009 inciphisa uxinzelelo kwiimodeli zeempuku.

  • Akukho sitofu

Ukuba une-trypanophobia, kukho iindaba ezimnandi kuwe. Ewe, i-SR9009 iyafumaneka kulawulo lomlomo. Akusekho zinaliti zibuhlungu, njengoko kunjalo nangakumbi amachiza atshisa ioyile.

 

Isikhokelo sokuThenga ngokugqibeleleyo se-2019 se-SR9009 sokwakha izihlunu ezingaphezulu

 

I-5.Half Ubomi be-SR9009

Ubomi besiqingatha se-SR9009 bufutshane njengeeyure ezine. Ngesi sizathu, kuya kufuneka uhlule idosi yakho kumanqanaba eeyure ezine ukuzinzisa ukungafumaneki kweziyobisi egazini.

 

I-6.SR9009 Umthamo kunye nokuKhwela

I-SR9009 idosi yeehenjisi kwizinto ezimbalwa. Oko kukuthi, unqwenela ukufezekisa nokuba ubandakanya ezinye izongezo kumjikelo wakho. Ngaphandle koko, isixa sobugqirha sikwaxhomekeke kwindlela umzimba wakho osabela ngayo.

Umthamo ophakathi yi-30mg ngemini, onokuthi uyihlule ngeendlela ezintathu ezahlukeneyo. Ngokwenyani, lo mayeza uthetha ukuba kufuneka uphathe ipilisi ngaphambi kokuba uthathe nakuphi na ukutya okuziikwere ezintathu. Endaweni yoko, ungasebenzisa isongezelelo emva kweeyure ezine.

Uninzi lwexesha, ukushiya i-SR9009 powder (1379686-30-2) idosi yokusebenza kwangoko inokuba ngumqobo, ngakumbi kubasebenzisi abanomonde. Ngubani onokuthatha iyeza ngamachaphaza iiyure ezine ngaphandle kokwenza ingxabano? Ke, ukuba awukhululeki kolu luhlu lwedosi, ungazimisela ukuyisebenzisa iyure ngaphambi kokwenza umthambo.

Umjikelezo weSR9009 uqhuba phakathi kweeveki ezisibhozo ukuya kwishumi elinambini. Kuba kukho amathemba okuba singanyamezeleki kwichiza, kufanelekile ukuthatha i-8-veki.

Eli chiza alichaphazeli isibindi okanye izintso. Nangona kunjalo, ungawakhusela la malungu ngokufaka ezinye izinto zokongeza ezikhuselekileyo ezinjenge-N2Guard kumjikelezo wakho we-SR9009.

 

I-7.Ingaba ufuna i-PCT ye-SR9009?

Ngokungafani nezinye izongezo, i-stenabolic ayifuni PCT (Thumela unyango ngoNyango) kuba iyeza alichaphazeli amanqanaba testosterone.

 

I-8.Iziphumo ezinokubakho ezichaseneyo kunye nomngcipheko wokuSetyenziswa kweSR9009

  • Utywala
  • Acne
  • intloko ebuhlungu
  • Acidx
  • ugwayi

Iimpawu ezingasentla ziya kuchaphazela kakhulu abaqalayo. Nje ukuba umzimba wakho uguqukele kwisongezo, iimpawu ziya kuphela. Nangona kunjalo, ukuba ngaba yimiphumela emibi ye-SR9009 iba mbi ngakumbi, kuya kufuneka uyilahle kwaye uthethe nogqirha wakho.

I-SR9009 inokwenzeka ukuba ibe mandundu imeko yamadoda ane-libido ephantsi okanye i-erectile dysfunctions. Ngamaxesha athile, isongezelelo sikhokelela kumanqanaba asezantsi e testosterone.

I-Stenabolic ayisiyo Isidakamizwa. Ke ngoko, ukuyithatha akuyi kuphazamisa inkqubo yehomoni. Amanqanaba akho e testosterone awayi kulahla, kwaye ichiza alomatize liza kwi-estrogen. Kubafazi, isongezelelo asizukukhokelela kumjikelo wokuya esikhathini ngokungaqhelekanga.

 

Isikhokelo sokuthenga esipheleleyo se-2019 sokwakha i-SR9009 SARM yokwakha umzimba

 

I-9.Stacking SR9009 yenye i-SARM

  • I-SR9009 vs. Ostarine

Kubekwa i-SR9009 nge I-Ostarine (MK-2866) Uya kufumana iziphumo ezizodwa, ngakumbi kwinqanaba lokubuyisela.

I-Ostarine, ngokwayo, yeyona SARM igqwesileyo yomjikelo wokubamba kunye nokusika. Nangona kunjalo, ukuba ufuna ukunyamezela okuphezulu, kuya kufuneka uyiklaze nge-SR9009. Ngexesha lokugcina, qinisekisa ukusebenzisa i-25mg ye-ostarine mihla le. Kwi-stenabolic, i-10mg iyakusebenza, kodwa kuya kufuneka uyithathe xa sele uza kubetha iziko lomzimba.

  • I-SR9009 vs. GW 501516

I-SR9009 kunye neGW501516 (Cardarine) kufutshane. Olunye uphononongo luze luthi le mixube mibini ibophelela kwii-receptors ezifanayo.

Njengoko sele uyazi, i-stenabolic ine-half-life ekhawulezayo, engayi kukuhlala usuku lonke. Ngokuchaseneyo, ukubakho kokufumaneka kwekhadiarine kufikelela kwiiyure ezingama-24. Ukudityaniswa kwezi zimbini kuya kukhokelela kwisiphumo se-24/7.

Ukuba usebenzisa i-SR9009 ecaleni kwe-GW501516, kuya kufuneka uthathele ingqalelo njengokongezwe ngaphambi kokusebenza. Ukuthetha oku, kuya kufuneka uphathe i-stenabolic kuphela ngeentsuku osebenza ngazo.

Xa kwisitaki se-SR9009, idosi yi-10mg kuphela, ekufuneka uyithathe kungekudala ngaphambi kokuba usebenze. Kwi-GW501516, iyeza elifanelekileyo ngu-20mg / ngosuku, oya kuthi ulilawule ngesidlo sakusasa.

 

Amava e-10.Builder

I-SR9009 yentengiso ikakhulu ijolise kubahlali abakha umzimba emva konyamezelo, ukunyuka kokusebenza komzimba, ukukhawulezisa ngokukhawuleza ukusebenza kunye nokwakha izihlunu ezomeleleyo.

Ukusuka kuvavanyo lweintanethi ezahlukeneyo, abasebenzisi baxela ukuba isongezelelo siphucule unyamezelo njengoko benokwenza imithambo eqatha ngaphandle kokuziva bediniwe. Kwabanye, ukunyuka kwamandla kunye nokunyusa amandla kwakukwinqanaba eliphezulu ngokukhawuleza emva kokuhambisa i-SR9009 powder (1379686-30-2).

Kwicala elingalunganga, abanye abasebenzisi bebengekhe bakhuphe isisu esiqhelekileyo rhoqo emva kweeyure ezine. Nangona kunjalo, abo basebenzisayo i-SR9009 stacks abayifumananga le nto iyinkxalabo kuba bathathe kuphela ukongeza xa besiya ejimini.

Abathengi abambalwa bavumile ukuba i-stenabolic ayibenzi bazive kakhulu. Ngaphandle kokungalali, akukho mntu wabonakala ebhalisa iziphumo ezibi ze-SR9009.

 

I-11.I-SR9009 Bioavava?

Kubekho uqikelelo lokuba i-SR9009 ine-zero bioavailability, ngakumbi kulawulo lomlomo. Nangona kunjalo, ndingayiphika ngokuzithemba le nto kuba ukuba isongezelelo besingafumaneki, ngekhe kubekho ziphumo zilungileyo ze-SR9009 emzimbeni womntu.

 

I-12.Uya kuyithenga phi i-SR9009

Abathengisi abangenakubalwa babeka i-SR9009 yokuthengisa. Nangona iivenkile ezikwi-Intanethi zikwindawo efanelekileyo yokuthenga izongezo, kuya kufuneka ulumke ungaweli lixhoba lemveliso yomgunyathi.

Ukuba ufuna i-stenabolic yamanqanaba oluntu, yifumane kumthengisi onesidima. Unokwenza iodolo nge AASraw.

 

I-13.SR9009 yokwakha umzimba

I-SR9009 powder (I-1379686-30-2) ityibilike kwimizi-mveliso yokwakha umzimba xa uphando luqinisekisile ukuba isongezelelo senze ukuba iimpuku zinezihlunu ezomeleleyo. Ngaphandle koko, babesebenza ngokubonakalayo, bebonisa ukusebenza kakuhle komzimba, kwaye babenomsindo kunangaphambili.

Abakhi bomzimba emva kobuninzi okanye ukusika baya kuxhamla ngokupheleleyo kwi-SR9009. Kwiimeko apho kuya kufuneka uqeqeshe ngakumbi, iyeza lonyusa izinga lokubetha kwentliziyo yakho, ngaloo ndlela unciphisa ubunzima kunye nokudinwa. Ngaphezu koko, isongezelelo sokwakha umzimba se-SR9009 sinciphisa ukuvuvukala kunye nokonakala kwezicubu ukuze inkqubo yokubuyisela kwimeko yesiqhelo ikhawuleze.

 

I-14.Conclusion

Isongezelelo sokwakha umzimba se-SR9009 sisebenzela ukuphucula ukusebenza. Ubuncinci, kukho uvavanyo olwaneleyo lokumisela le nyaniso kunye nokuphononongwa komsebenzisi okuqinisekileyo kwemveliso.

Nangona kunjalo, ukusebenza ngokukuko kweli chiza ibilithambo lembambano phakathi kwezazinzulu kunye nabaphandi kunye nososayensi ngokubanzi. Umzekelo, bekukho ii-anecdotes zokuba i-SR9009 yomlomo yokufumaneka komzimba ayifumaneki. Ewe, andinqweneli ukwenza igqwetha longendawo, kodwa i-95% yabasebenzisi be-stenabolic bayakuqinisekisa ukusebenza kwayo. Ngaphandle koko, kuya kufuneka ubuze ukuba kutheni imibutho echasene ne-doping inokuba nesibindi sokuthintela ukusetyenziswa kwayo kwiimbaleki xa into ingasebenzi kakuhle.

Qaphela ukuba iziphumo ze-SR9009 zibakho xa usebenza rhoqo ngelixa usenza ukutya okusempilweni. Kulumkele ukutya okunamafutha, iikhalori, kunye nokucekeceke ekutshayeni nasekuseleni.

 

Ucaphulo

  1. Cho, H., Zhao, X. et al. (2012). Ukulawulwa kokuziphatha ngokujikeleza kwe-Circadian kunye neMetabolism ye-REV-ERBα kunye ne-REV-ERBβ. I-Gene Expression Laborator, iSalk Institute yezifundo zebhayoloji.
  2. IMorioka, N., Zhang, FF, Tomori, M., Hisaoka-Nakashima, K., Saeki, M., kunye noNakata, Y. (2016). Ukuvuselela i-NVNRB ye-Receptor ye-Nuclear ilawula i-Tumor Necrosis Factor-Ekwabonisa ukuHanjiswa kweeMolekyuli kwi-C6 Iiseli ze-Astroglial.
  3. Amakhaya, i-PG, iBrandon-Warner, i-E, et al. (2016). I-Rev-Erb Agonist kunye ne-TGF-β Ngokunjalo zichaphazela i-Autophagy kodwa ngokungafaniyo kulawula i-Hepatic Stellate Cell Fibrogenic Phenotype. Int J Biochem Cell Biol.
  4. UDodson, B. (2013). Izixhobo eziMtsha zokulinganisa iziBonelelo eziNzuzo zokuzivocavoca. LezeMpilo kunye neNtlalo.
  5. Woldt, E., Sebti, Y. Et al. (2013). Uhlaziyo lwe-Erbα Modulates Muskeleal Muscle Oxidative Capacity ngokulawula iMitochondrial Biogeneis kunye ne-Autophagy. Ijenali yoNyango lweNdalo.
  6. USulli, G., Rommel, A., et al. (2018). I-activation ye-Pharmacological ye-REV-ERB yi-Lethal in Cancer kunye ne-Oncogene-Indosed Senescence. Indalo (Ijenali yangaphakathi yeSayensi).
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