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I-Crizotinib powder (877399-52-5)

Akukho kalo
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi
SKU: 877399-52-5. Udidi:

I-AASraw inokusetyenziswa kunye nokukwazi ukuvelisa kwigram ukuya kwinqanaba le-Crizotinib powder (877399-52-5), phantsi kolawulo lweCGMP kunye nolawulo lwekhwalithi ephezulu.

Ingcaciso yeMveliso

Crizotinib powder ividiyo


Crizotinib powder Abalinganiswa basisiseko

igama: Crizotinib powder
CAS: 877399-52-5
I-molecular Formula: C21H22Cl2FN5O
Isisindo somzimba: 450.343
Melt Point: 197-203 ° C
Isitoreji sokugcina: RT
umbala: i-white-powder-yellow yellow powder


I-Crizotinib powder ekusebenziseni unyango lomhlaza

Amagama

I-crizotinib powder, i-Xalkori powder

Ukusetyenziswa kweCrizotinib powder

I-Crizotinib powder yimiyeza yomhlaza ephazamisa ukukhula nokusabalala kwamaseli omhlaza emzimbeni. I-Crizotinib powder isetyenziselwa ukunyanga umhlaza ongaselula umhlaza wamaphaphu.

I-Crizotinib powder yi-tyrosine kinase inhibitor. Isebenza ngokukhusela i-enzyme ebizwa ngokuthi i-plastiki lymphoma kinase (ALK). I-Crizotinib powder isebenza kuphela kumaseli omhlaza one-ALK. Mayelana ne-5 kubantu be-100 (5%) kunye ne-NSCLC banalo. Ibizwa ngokuba yi-ALK isifo esihle.

Ugqirha wakho unokuncoma ukuba ube ne-Crizotinib powder ukuba uye waphila umhlaza wesifo somhlaza womnxeba ongeyonto encinci.

I-XALKORI iifomsile ze powder zixhaswa njengama-capsules e-hard shell-shell equkethe i-250 mg okanye i-200 mg ye-Crizotinib powder kunye ne-colloidal dioxide, i-microcrystalline cellulose, i-calcium phosphate, i-sodium starch i-glycolate, i-stearate ye-magnesium, ne-gelatin shells capsule njengezixhobo ezingasebenzi.

Iincoko ze-shell opaque capsule shell ziqukethe i-gelatin, i-titanium dioxide, ne-red iron oxide. Iimpawu zegolum e-white opaque shells ziqukethe i-gelatin kunye ne-titanium dioxide. Inkino yokuprinta iqukethe i-shellac, i-propylene glycol, isisombululo esinamandla se-ammonia, i-potassium hydroxide kunye ne-black iron oxide.

I-crizotinib powder yi-capsule. Uyawugwinya ngokupheleleyo ngeglasi yamanzi. Unako ukufumana okanye ngaphandle kokutya.

Kumele uthathe iifomsile ngokwemiyalelo yakho ugqirha okanye othemistri anika yona.
Kufuneka uthathe umthamo ofanelekileyo, kungekho ngaphezulu okanye ngaphantsi.

Ungalokothi uyeke ukuthatha isidumbu somhlaza ngaphandle kokuthetha nengcali yakho yokuqala.

Uyithatha kabini ngosuku - kanye ekuseni kwaye kanye ngokuhlwa.

Ngokuqhelekileyo uqhubeka uyithatha ixesha elide liqhubeka lisebenza, ngaphandle kokuba iziphumo ezibi zibi kakhulu.

Unayo iimvavanyo zegazi ngaphambi kokuqala unyango kwaye ngexesha lonyango lwakho. Bajonga amanqanaba akho eeseli zegazi kunye nezinye izinto egazini. Bajonga kwakhona ukuba isibindi sakho kunye neentso zisebenza njani.

Isexwayiso kwi-Adrafinil

Iidakamizwa zentsholongwane zingakwazi ukusebenzisana namanye amayeza kunye nemveliso yemveliso. Tshela ugqirha wakho okanye umasipala malunga nawaphi na amayeza owathathayo. Oku kubandakanya iivithamini, isongezelelo semfuyo kunye neendlela zokulungisa izixhobo.

Gweba iidipefruit kunye nejusi yamagilebhisi ngenxa yokuba banokunyusa imiphumo emibi.

Ukukhulelwa nokukhulelwa
Esi sidakamizwa singalimaza umntwana okhulayo kwisibeleko. Kubalulekile ukuba ungakhulelwa okanye utata umntwana xa unyango le nkunkuma kwaye ubuncinane kwiinyanga ze-3 emva koko. Thetha ugqirha okanye umongikazi malunga nokuqhawula ngokuchanekileyo ngaphambi kokuqala unyango.

Ukhula
Asazi ukuba lo unyango lunokuchaphazela njani ukuzala. Awukwazi ukukhulelwa okanye utata umntwana emva kokunyanga kwesi siza. Xoxa nodokotela wakho ngaphambi kokuba uqale unyango xa ucinga ukuba unokufuna ukuba nomntwana kwixesha elizayo.

Amanye amadoda angakwazi ukugcina isidoda ngaphambi kokuqala unyango. Abanye abesifazana basenokukwazi ukugcina amaqanda okanye imibusi ngaphambi kokonyango.

Ukuncelisa
Musa ukuncelisa ngethuba lo unyango ngenxa yokuba isilwanyana singenayo ubisi lwakho lwebele.

Unyango kwezinye iimeko
Njalo xelela abanye oogqirha, abahlengikazi, amayeza kunye namazinyo ukuba unalo unyango ukuba ufuna unyango kunoma yini enye, kuquka neengxaki zamazinyo.

Ukugonywa
Musa ukugonywa ngeigciwane eziphilayo ngelixa unyango kwaye ubuncinane kwiinyanga ze-6 emva koko.

Unga:

-kunye ukugonywa, kodwa abanokukunika ukhuseleko olunjalo njengesiqhelo
-ba nomgomo wokugonya umkhuhlane
-ngabonxibelelana nabanye abantu abaye bafumana iigciwane eziphilayo njengamayeza

Gweba ukunxibelelana nabantu abaye bafumana iigciwane eziphilayo ezithathwe ngomlomo (izitofu zomlomo). Oku kubandakanya ukugonywa kwe-rotavirus ezinikezelwe iintsana. Intsholongwane ingumchamo womntwana ukuya kwiiveki ze-2 kwaye unokukugula. Ngoko, gwema ukutshintsha ii-nappies kwiiveki ze-2 emva kokugonya xa kunokwenzeka. Okanye ugqoke iiglavu ezilahlayo kwaye uhlambe izandla emva koko.

Kufuneka kwakhona ukuba ugweme nabani na oye waba nepolori yomlomo okanye ukugonywa kwe-typhoid kungekudala.

I mi yalelo

I-XALKORI powder (Crizotinib powder) ngumlomo we-receptor tyrosine kinase inhibitor. Ifomula yeCrizotinib powder yiC21H22Cl2FN5O. Isisindo somzimba sisi450.34 daltons. I-crizotinib powder ichazwa ngamachiza njenge-RN -3- [1- (2,6-Dichloro-3-fluorophenyl) ethoxy] -5- [1- (piperidin-4-yl) -1H-pyrazol-4-yl] pyridin- 2-amine.

I-Crizotinib powder yimibala emhlophe ephuzi ephuzi kunye ne-pKa ye-9.4 (ciperidinium cation) kunye ne-5.6 (pyridinium cation). I-solzotility ye-Crizotinib powder kwi-media media iyanciphisa ngaphezu kwe-pH 1.6 ukuya kwi-pH 8.2 ephezulu kune-10 mg / mL ukuya ngaphantsi kwe-0.1 mg / mL. I-log ye-coefficient (u-octanol / amanzi) kwi-pH 7.4 yi-1.65.

Fumana uncedo lwezonyango lwexesha loxakeka ukuba unayo nayiphi na le miqondiso yempendulo yokumelana nomzimba: imihlathi; ukuphefumula okunzima; ukuvuvukala kobuso bakho, imilomo, ulwimi, okanye umqala.

Yeka ukusebenzisa i-Crizotinib powder uze ubize ugqirha wakho kanye xa unesiphumo esibi sempembelo efana nale:

utywala obunzima, ukuphazamiseka, ukukhawuleza okanye ukuphazamisa intliziyo;
iingxaki zombono ezifana nombono otyhafisiweyo, ukwanda kwamehlo akho ekukhanyeni, okanye ukubona ukukhanya kokukhanyisa okanye "iiflethi";
intlungu yesifuba, ukukhwehlela oomileyo okanye ukukhwehlela nge-mucus, ukuvutha, ukuva kancinci;

I-Crizotinib powder Powder

I-10grams encinci.
Uphando malunga nobukhulu obuqhelekileyo (ngaphakathi kwe-1kg) lungathunyelwa kwiiyure ze-12 emva kokuhlawula.
Ukwenza umlinganiselo omkhulu (ngaphakathi kwe-1kg) ungathunyelwa kwimihla yokusebenza ye-3 emva kokuhlawula.

Crizotinib powder Marketing

Ukubonelelwa kwikamva elizayo.


Indlela yokuthenga i-Crizotinib powder evela kwi-AASraw

1.Qhagamshelana nathi nge-imeyile yethu inkqubo yophando, okanye i-skype ye-intanethiummeli wenkonzo yamakhasimende (CSR).
2.Ukusibonelela ngobuninzi bakho kunye neadesi.
I-3.I-CSR yethu iya kukunika isingeniso, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuhambisa kunye nomhla wokufika oqikelelwayo (i-ETA).
I-4.Inkokhelo eyenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ze-12 (Ukuze ulandelwe ngaphakathi kwe-10kg).
5.Goods zifunyenwe kwaye zinike izimvo.


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HNMR

I-Crizotinib powder (877399-52-5) I-AASRAW HNMR

Recipes

Crizotinib powder Raw Powder Recipes

Ukubuza ummeli wethu ummeli (Representative Representative) (CSR) ngeenkcukacha, ngokubhekiselele kuyo.

Iziqulatho kunye nokuqulunqwa kwemveliso

I-crizotinib powder (i-877399-52-5) yenze i-agent anti-cancer

ngokutsha 1 ngenxa I-Crizotinib powder (877399-52-5)

  1. ikaliwe 5 ngaphandle 5

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    I-Crizotinib powder ingumongameli

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