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I-Eplerenone powder (107724-20-9)

Akukho kalo
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi
SKU: 107724-20-9. Udidi:

I-AASraw ikunye kunye nokukwazi ukuvelisa kwigram ukuya kwinqanaba le-Eplerenone powder (107724-20-9), phantsi kommiselo weCGMP kunye nolawulo lwekhwalithi ephezulu.

Eplerenone powder ngumdlali ochasene ne-aldosterone ngokuthe ngqo kwi-receptor ye-mineralocorticoid kune-spironolactone, enobudlelwane obungaphantsi kweprogesterone, i-androgen, kunye ne-receptors ye-glucocorticoid. Ukuphuculwa kokusinda kwezigulane ezizinzileyo kunye ne-left syriclic dissyction function (i-fraction ye-ejection <40%) kunye nobungqina beklinikhi yokusilela kwintliziyo emva kwesifo se-myocardial acute.

Ingcaciso yeMveliso

Eplerenone powder ividiyo


I-Eplerenone powder ezisemqoka

igama: Eplerenone powder
CAS: 107724-20-9
Ukucoceka: I-99% min (HPLC)
I-molecular Formula: C24H30O6
Isisindo somzimba: 414.49
EINECS: 1308068-626-2
Iintetho: Ukukhulelwa-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-lactone esethyl ester; EPLERENONE 98%; EPLERENONE USP STANDARD; Elperenone; EplerenoneC24H3006; i-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo, γ-lactone, i-methyl ester (7 α, 11 α, 17 α); I-EPLERENONE NE-N-1 I-INTERMEDIATE; i-epoxymexrenone
Melt Point: 241-243 ° C
Alpha: D + 5 ° (c = 0.437 kwi-chloroform)
Isitoreji sokugcina: Gcina kwi RT
I-DMSO enamandla i-soluble2mg / mL, icacile (ifudumele)
umbala: I-White ukuya kumhlophe i-crystalline powder


Oko Ufuna Ukwazi Ku-Eplerenone powder

igama

I-Eplerenone powder (AASraw)

Yintoni i-Eplerenone powder

I-Eplerenone powder ngumlomo we-aldosterone owamkela umlomo ofana ne-spironolactone ye-diuretic, ingasetyenziselwa yodwa okanye idibene namanye amayeza ukuphatha uxinzelelo lwegazi oluphezulu. Isebenza ngokuthintela ikhemikhali (aldosterone) emzimbeni wakho ekunciphiseni umlinganiselo we-sodium namanzi umzimba ugcine. Ukunciphisa uxinzelelo lwegazi oluphezulu kunceda ukukhusela izibetho, ukuhlasela kwentliziyo kunye neengxaki zeengtso. Kwakhona kusetyenziselwa ukuphatha ukungaphumeleli kwentliziyo kwintliziyo emva kwesifo senhliziyo. Ngaphandle koko, i-Eplerenone powder ihlolisiswa njengonyango lwe-serous retinopathy.

Ingakanani i-Eplerenone powder ithatyathwe kakhulu

Ukusebenzisa i-Eplerenone powder njengokuba ugqirha ugqirha wakho, ngokuqhelekileyo kanye okanye kabini imihla ngemihla. Landela izikhokelo kwiileyibrari yakho yesigunyaziso, sebenzisa le mayeza rhoqo ukuze ufumane inzuzo enkulu kuyo. Khumbula ukuyisebenzisa ngexesha elifanayo (ngamnye) ngosuku. Umyinge usekelwe kwimeko yakho yonyango (uxinzelelo oluphezulu lwegazi, ukungaphumeleli kwentliziyo), impendulo kwonyango kunye nezinye iimichiza onokuzithatha. Qiniseka ukuxelela ugqirha wakho kunye nekhemistiki malunga nayo yonke imveliso oyisebenzisayo (kubandakanya iziyobisi zonyango, izidakamizwa ezingekho phantsi kokubhaliswa, kunye nemveliso yemveliso) .Ugqirha wakho angaphinda atshintshe umthamo wakho ukuqinisekisa ukuba ufumana iziphumo ezilungileyo.Ifowuni enye ingathathwa kunye okanye ngaphandle kokutya. Ukuze uqiniseke ukuba eli liyeza lisiza imeko yakho kwaye alibanga iziphumo eziyingozi, uxinzelelo lwegazi luya kufuneka luhlolwe rhoqo. Amazinga akho e-potassium aya kufuneke ahlolwe kunye nokuhlolwa kwegazi rhoqo. Tyelela ugqirha wakho rhoqo.

Ukuba uphathwa unyango lwegazi oluphezulu, qhubeka usebenzisa le myeza nokuba uziva kakuhle. Uxinzelelo lwegazi oluphezulu kaninzi alubonakali. Unokudinga ukusebenzisa imishanguzo yegazi ngenxa yobomi bakho bonke.

Gcina kwiqondo lokushisa elisekude kumanzi kunye nobushushu.

Isilumkiso kwi-Eplerenone powder

I-Eplerenone powder kufuneka isetyenziswe ngokuqapha kwi:

izigulane ezineengxaki zesifo okanye isibindi, abo bathatha i-lithium (ngokubanzi banikwe i-bipolar disorder), kunye nalabo bathatha i-tacrolimus okanye i-ciclosporin (esetyenziselwa ukuthintela ukulahlwa komzimba emva kokutshintshwa okanye ukunyanga iimeko ze-eczema).
Akufanele isetyenziswe ku:

izigulane ezithintekayo (i-hypersensitive) kwi-Eplerenone powder okanye nakwezinye izithako kwiyeza (ezifana ne-lactose), izigulane ezinamaqondo aphakamileyo e-potassium egazini (hyperkalaemia), abo baneesifo esifutshane, izifo, abantwana, izigulane ezithatha amayeza okusuleleka kwintsholongwane (ketoconazole okanye itraconazole), unyango lwe-anti-antial (i-nelfinavir okanye i-ritonavir), i-antibiotics (i-clarithromycin okanye i-telithromycin), i-nefazodone yokudandatheka, okanye iziyobisi ukunceda umzimba ukuba ungabikho umbane ogqithiseleyo njengokwenziwa kwe-potassium i-diuretics kunye 'neeseti zetyuwa' (izongezelelo ze potassium).

Ngaphambi kokuba uthathe i-Eplerenone powder, vumela ugqirha wakho ukuba uyazi, okanye wakha waphila:
Diabetes

  • Ngaba umsebenzi wesifo osweleyo (isifo sesifo)
  • Ukunyuka kwamanzi kwiphina iyeza
  • Amazinga aphezulu e-potassium egazini lakho (hyperkalemia)
  • isifo esibi kakhulu (isifo sesibindi)
  • I-cholesterol ephakamileyo okanye amanqanaba e-triglyceride
  • I-Gout (uhlobo lwe-arthritis ebangelwa i-uric acid crystals).

Izigulane ezithintekayo (i-hypersensitive) kwi-Eplerenone powder okanye nakwezinye izithako kwiyeza (ezifana ne-lactose), izigulane ezinamaqondo aphakamileyo e-potassium egazini (hyperkalaemia), abo banesifo esifutshane nesifo senhliziyo, abo banesibindi esikhulu izifo, abantwana, izigulane ezithatha amayeza okusuleleka kwintsholongwane (ketoconazole okanye itraconazole), unyango lwe-anti-antial (i-nelfinavir okanye i-ritonavir), i-antibiotics (i-clarithromycin okanye i-telithromycin), i-nefazodone yokudandatheka, okanye iziyobisi ukunceda umzimba ukuba ungabikho umbane ogqithiseleyo njengokwenziwa kwe-potassium i-diuretics kunye 'neeseti zetyuwa' (izongezelelo ze potassium)

Ugqirha wakho unokucetyisa ukuba usebenzise isondlo esontsi ephantsi ngexesha lakho unyango kunye ne-Eplerenone powder. Landela le miyalelo ngokucokisekileyo. Tshela ugqirha wakho ukuba uthatha le nyeza ngaphambi kokuba ube nayiphi na inkqubo yezokwelapha okanye yamazinyo. Gcina zonke izithuba kunye nogqirha wakho kunye nelabhoratri ngelixa usebenzisa i-Eplerenone powder. Umboneleli wakho wezempilo uyakufuna ukwenza iimvavanyo eziqhelekileyo ukujonga impendulo yomzimba wakho kule chiza. Ezinye iziyobisi akufanele zisetyenziswe kunye ne-Eplerenone powder. Tshela ugqirha wakho ukuba uthatha naziphi na ezi zilandelayo:

  • Midamor (amiloride)
  • Dyrenium (triamterene)
  • INizoral (ketoconazole)
  • Ukukhulelwa kunye ne-Eplerenone powder
  • Aldactone (spironolactone)
  • Amiloride kunye ne-hydrochlorothiazide
  • I-Sporanox okanye i-Onmel (itraconazole)
  • I-Aldactazide (i-spironolactone ne-hydrochlorothiazide)
  • Dyazide okanye Maxzide (triamterene kunye ne-hydrochlorothiazide)
  • Izithako zePotassium, okanye izitishi zetyuwa eziqukethe i-potassium

Ngaphambi kokuqala kwi-Eplerenone powder, xela ugqirha wakho ukuba ukhulelwe, okanye uceba ukukhulelwa. Uya kufuneka uxoxe ngezibonelelo kunye nobungozi bokuthatha eli gama ngexesha lokukhulelwa. Njengoko kungaziwa ukuba i-Eplerenone powder iyadlula ubisi lwebele. Musa ukuncelisa umntwana ngelixa usebenzisa le mayeza.

Eplerenone powder

I-10grams encinci.
Uphando malunga nobukhulu obuqhelekileyo (ngaphakathi kwe-1kg) lungathunyelwa kwiiyure ze-12 emva kokuhlawula.
Ukwenza umlinganiselo omkhulu (ngaphakathi kwe-1kg) ungathunyelwa kwimihla yokusebenza ye-3 emva kokuhlawula.

Eplerenone powder Ukuthengisa

Ukubonelelwa kwikamva elizayo.


Indlela yokuthenga i-Eplerenone powder kwi-AASraw

1.Qhagamshelana nathi nge-imeyile yethu inkqubo yophando, okanye i-skype ye-intanethiummeli wenkonzo yamakhasimende (CSR).
2.Ukusibonelela ngobuninzi bakho kunye neadesi.
I-3.I-CSR yethu iya kukunika isingeniso, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuhambisa kunye nomhla wokufika oqikelelwayo (i-ETA).
I-4.Inkokhelo eyenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ze-12 (Ukuze ulandelwe ngaphakathi kwe-10kg).
5.Goods zifunyenwe kwaye zinike izimvo.

ISIQINISEKISO NESIBONELELO:

Le nto ithengiselwe uKwenziwa koPhando kuphela. Imigaqo yokuthengisa Faka isicelo. Ayisetyenziselwa uBuntu, okanye oNyango, iZilwanyana, okanye abaNtu.


IAAA

I-COA 107724-20-9 I-Eplerenone powder i-AASRAW

HNMR

107724-20-9 Eplerenone I-HNMR ye-AASRAW

Recipes

Eplerenone powder Recipes

Ukubuza ummeli wethu ummeli (Representative Representative) (CSR) ngeenkcukacha, ngokubhekiselele kuyo.

Iziqulatho kunye nokuqulunqwa kwemveliso