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I-Trastuzumab (180288-69-1)

Akukho kalo
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi
SKU: 180288-69-1. Udidi:

I-AASraw inokusetyenziswa kunye nokukwazi ukuvelisa kwigram ukuya kwi-Trastuzumab (i-CAS 180288-69-1), phantsi komgaqo weCGMP kunye nolawulo lwekhwalithi ephezulu.

Trastuzumab powder isetyenziswe kunyango lwe-HER2-positive umdlavuza webele. I-HER2 iprotheni yokugqithisa ingqalelo kwi-25% -30% yeengqungquthela zebele zesifuba. I -trastuzumab ibonisiwe, kwiimbini ze-vitro kunye nezilwanyana, ukuvimbela ukwandisa kwezidumbu zezilwanyana ezithatha i-HER2.

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Ingcaciso yeMveliso

Ividiyo yeTrastuzumab


Trastuzumab Abalinganiswa basisiseko

igama: Trastuzumab
CAS: 180288-69-1
I-molecular Formula: C10H14N6O5
Isisindo somzimba: 298.25536
Melt Point: 61-71 ° C
Isitoreji sokugcina: 2-8 ° C
umbala: Powder


Ukusetyenziswa kweTrastuzumab (180288-69-1) kumjikelezo we-steroids

Amagama

I-Trastuzumab (i-CAS 180288-69-1), igama lohwebo ngu-Herceptin.

Ukusetyenziswa kweTrastuzumab

I-Trastuzumab inikezwa ngokungenisa ngaphakathi kwi-vein (intravenous, IV). Inqanaba lokuqala linikwe imizuzu ye-90. Ukuba izilingo zokulondolozwa ngokulandelelanayo ziyakunikwa imizuzu engama-30.
Isixa seTrastuzumab (180288-69-1) esiya kufumana sincike kwiimeko ezininzi, kubandakanya ubude bakho nobukhulu bakho, impilo yakho jikelele okanye ezinye iingxaki zempilo, kunye nohlobo lomhlaza okanye imeko ephathwayo. Ugqirha wakho uya kugqiba umthamo wakho kunye neshedyuli.

Isexwayiso kwi-Trastuzumab

Impembelelo engundoqo kodwa engaqhelekanga yeTrastuzumab inokuphazamiseka nentshukumo yepompo. Izehlo iingxaki zentliziyo (ukusilela intliziyo) ukwandisa abantu abanesifo sentliziyo okanye eminye imiba efana radiation esifubeni, ubudala phambili, kunye nokusetyenziswa nezinye iziyobisi intliziyo-ityhefu (ezifana doxorubicin kunye cyclophosphamide). Ugqirha wakho unokujonga umsebenzi wakho wenhliziyo ngaphambi kokuba uthathe nayiphi na i-Trastuzumab kwaye uya kujonga intliziyo yakho ngokukhawuleza ngexesha lonyango. I-Trastuzumab (i-180288-69-1) ingasuswa xa kukho ukubonakala kweempawu zentliziyo.

I mi yalelo

Amanqindi e-Monoclonal ayingxaki entsha yonyango lomhlaza. Ama-antibodies ayingxenye yesistim somzimba. Ngokuqhelekileyo, umzimba wenza ama-antibodies ekuphenduleni kwi-antigen (njengeprotheyini kwintsholongwane) engena emzimbeni. Ama-antibodies anamathele kwi-antigen ukwenzela ukuwuphawula ngokutshabalaliswa ngumzimba womzimba. Kwi-laboratory, izazinzulu zihlalutya ama-antigens athile kummandla weeseli zomhlaza (ekujoliswe kuyo) ukufumanisa iprotheni ukufanisa i-antigen. Emva koko, usebenzisa iipilisi kunye neeprotheni zomntu, izazinzulu zisebenza ukudala i-antibody ekhethekileyo eya kufakelwa kwi-target target antigen. Ama-antibodies aya kufakelwa kwii-antigens ezifanayo ezifana nesitshixo sifana nekhikhi. Le teknoloji ivumela unyango ukujolisa kwiiseli ezithile, kubangele ubuncinane besifo kwiiseli eziphilileyo. Ulwaphulo lwe-antioclonal antibody lungenziwa kuphela ngeengcingo apho i-antigens (kunye ne-antibodies) echongiwe.

I-Trastuzumab isebenza ngokujolisa kwi-HER2 / neu receptor kumaseli omhlaza. Umgubo weHER2 uvelisa i-protein receptor kwi-cell surface ebonisa ukukhula kweeseli ngokuqhelekileyo ngokuxelela iseli ukwahlula nokuphindaphinda. Ezinye izicubu zesifuba somhlaza zininzi kakhulu i-HER2 (HER2 / neu ngokugqithiseleyo), ezibangela ukuba iiseli zihlukane kwaye zande ngokukhawuleza. I-Trastuzumab (180288-69-1) ifakela kwi-HER2 receptors ukukhusela iiseli ukuba zande, zikhusele ukukhula komhlaza kunye nokunciphisa ukuqhubeka komhlaza. Inokuphinda isebenze ngokukhuthaza indlela yokuzivikela.


Indlela yokuthenga iTrasstuzumab ukusuka ku-AASraw

1.Qhagamshelana nathi nge-imeyile yethu inkqubo yophando, okanye i-skype ye-intanethiummeli wenkonzo yamakhasimende (CSR).
2.Ukusibonelela ngobuninzi bakho kunye neadesi.
I-3.I-CSR yethu iya kukunika isingeniso, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuhambisa kunye nomhla wokufika oqikelelwayo (i-ETA).
I-4.Inkokhelo eyenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ze-12 (Ukuze ulandelwe ngaphakathi kwe-10kg).
5.Goods zifunyenwe kwaye zinike izimvo.


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ngokutsha 1 ngenxa I-Trastuzumab (180288-69-1)

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