ISouth Africa Delivery, iDaily Domestic Delivery, I-European Domestic Delivery

Amandla eTrilostane Powder (13647-35-3)

Akukho kalo SKU: 13647-35-3. Udidi:

I-AASraw ikunye nokudalwa kunye nobuchule bokuvelisa ukusuka kwigram ukuya kwi-oda ye-Trilostane Powder (13647-35-3), phantsi kommiselo weCGMP kunye nenkqubo yokulawula umgangatho olandelelweyo.

Ingcaciso yeMveliso

I-Trilostane Powder (13647-35-3) ividiyo


I-Trilostane Powder (13647-35-3) Sukufunyanwa:

Ulwakhiwo lweKhemikhali: Igama lemveliso: Trilostane
Cas No.: 13647-35-3
I-Molecular Formula: C20H27NO3
Isisindo somzimba: 329.43
Umgangatho: Ngaphakathi
Ukugcina: Emile, emnyama kunye ne-0 - 4 C ngexesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (inyanga ukuya kwiminyaka).
Amaxwebhu (COA & HPLC njl.njl): iyafumaneka

I-Trilostane Powder (13647-35-3) Dkubhala:

I-Trilostane powder yi-inhibitor ye-3β-hydroxysteroid dehydrogenase esetyenziswa kunyango lwe-Cushing's syndrome kunye ne-hyperaldosteronism eyintloko. Ezi zombini ziimeko zokuphazamiseka apho amaxabiso amakhulu e-corticosteroid aveliswa emzimbeni. IiCorticosteroids zibalulekile emzimbeni ukuze zisebenzise i-carbohydrate, amafutha kunye neeproteni kunye nokuphendula okuqhelekileyo kuxinzelelo. Ziyimfuneko kwakhona kummiselo wetyuwa kunye nokulingana kwamanzi emzimbeni. I-Trilostane powder inceda ukukhusela ukuveliswa kwe-corticosteroids, ukulawula iimpawu ezihambelana noku kuphazamiseka.

I-Trilostane powder inokuba luncedo kunyango lomhlaza webele oye wabuyela kubasetyhini abaye badlula ngenxa yokuyeka ukuya esikhathini.

Kwagqitywa nje ukuvunywa ngo-2008 kunyango lwesifo sikaCushing (hyperandrenocorticism) ezinjeni. Ikwa sisiyobisi sokuqala esamkelweyo sokunyanga ukubanjiswa kwezinja kunye nokuxhomekeka kwi-adrenal. Esi siyobisi sigunyazisiweyo sisebenza ngokuyekisa ukuveliswa kwe-cortisol kumadlala adrenal.

Imbekiselo:

  • 1: Midence JN, Drobatz KJ, Hess RS. Ukuqokelelwa kweCortisol kwiNja ezilawulwa kakuhle ngeHyperadrenocorticism Iqhutywa ngeTrimostane. J Vet Ngaphakathi kwiMed. Ngo-2015 i-Nov; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. I-PubMed PMID: 26374943.
  • I-2: I-Fracassi F, i-Corradini S, i-Floriano D, i-Boari A, i-Aste G, i-Pietra M, i-Bergamini PF, i-Dondi F. Iimpawu zengqondo zokusinda ezinjeni ezine-hypercortisolism exhaswa yipituostane. Vet Rec. I-2015 Jan 10; 176 (2): 49. Doi: 10.1136 / vr.102546. Epub 2014 Aug 28. I-PubMed PMID: 25170036.
  • I-3: I-Bonadio CM, iFeldman EC, iCohen TA, iKass PH. Ukuthelekisa iziphumo ze-adrenocorticotropic ye-hormone yokunyusa iziphumo zaqala kwi-2 ngokuchasene neeyure ezi-4 emva kolawulo lwe-trilostane kwizinja ezinenququism ye-hyperadrenocorticism. J Vet Ngaphakathi kwiMed. Ngo-2014 uJul-Aug; 28 (4): 1239-43. doi: 10.1111 / jvim.12357. Epub 2014 Meyi 26. I-PubMed PMID: 24863172.