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I-Ulipristal Acetate Powder (26784-99-4)

Akukho kalo SKU: 26784-99-4. Udidi:

I-AASraw ine-synthesis kunye nobuchule bokuvelisa ukusuka kwigram ukuya kwi-oda ye-Ulipristal Acetate Powder (26784-99-4), phantsi kommiselo weCGMP kunye nenkqubo yokulawula umgangatho.

Ingcaciso yeMveliso

I-Ulipristal Acetate Powder (26784-99-4) ividiyo


I-Ulipristal Acetate Powder (26784-99-4) Sukufunyanwa:

Ulwakhiwo lweKhemikhali: Igama lemveliso: I-Ulipristal Acetate (i-Ulipristal Acetate ephakathi)
Cas No.: 26784-99-4/126690-41-3/54201-84-2
I-Molecular Formula: C30H37NO4
Isisindo somzimba: 475.62
Iintetho: 3,20-bis-Ethylenedioxy-5α,17α-dihydroxy-11β-(4-N,N-dimethylaminopheynl)-19-norpregn-9-ene; 3,20-bis-Ethylenedioxy-19-norpregna-5(10)9(11)dien-17-ol
Ukugcina: Gcina kwiqondo lokushisa kwigumbi kude ukukhanya kunye nokufuma.
Amaxwebhu (COA & HPLC njl.njl): Iyafumaneka

I-Ulipristal Acetate Powder (26784-99-4) Dkubhala:

I-Ulipristal acetate yamkelwa ukusetyenziswa kwezonyango e-United States ngo-2010. Ikuluhlu lwe-World Health Organisation Uluhlu lweeMedical Essential, amayeza asebenza ngokukhuselekileyo nawayimfuneko kwinkqubo yezempilo.E-United Kingdom ixabisa i-NHS malunga neepawundi ezili-17 nge Ikhosi yokulawulwa kokungxamisekileyo kokuzalwa kuka-2015.Ukuphucula ukufikelela, abanye bacebisa ukuba bonke abanokukhulelwa banikwe amayeza ukuba bawasebenzise xa kufuneka.

I-Ulipristal acetate powder yeyokukhetha kwimodyuli ye-proepterone receptor ekhethiweyo, intsholongwane kunye nefuthe le-agonistic kwi-progesterone receptor. Yona kunye nomzimba we-progesterone receptor yokubopha ukuthintela i-progesterone kunye neeprogesterone receptors. I-acetic acid yokusebenza kwayo kuxhomekeke kwixesha lethu lokuhanjiswa kumjikelo wokuya esikhathini. Ukuhanjiswa kwe-hyperplasia ephakathi ye-follicular kunokuthintela i-folliculogeneis kunye nokunciphisa uxinzelelo lwe-estradiol. Ulawulo lwe-luteinizing hormone peak kwii-follicles zokubambezeleka okubambekayo kwiintsuku ezi-5 ~ 9. I-Corpus luteum yolawulo lwakwangoko yokulibaziseka ekuthomalalisweni kwe-endometrial, kodwa inokwenza unciphiso lobungakanani bokuphela kwe-0.6 ± 2.2mm (kuthetha ± SD).

Imbekiselo:

  • Ifomathi yesizwe yaseBritane: BNF 69 (69 ed.). Umbutho wezonyango waseBritane. 2015. iphe. 510, 560. I-9780857111562.
  • I-Trussell, James; URaymond, uElizabeth G .; UCleland, Kelly (ngo-2014). "Ukuthintela ukukhulelwa okukhawulezileyo: Ithuba lokugqibela lokuthintela ukukhulelwa okungalindelekanga" (iPDP). Ukufundwa okwethutyana eMthethweni kunye nezobuLungisa boLuntu. 6 (2): 7–38. Archived (PDF) ukususela nge-23 Septemba 2010.
  • IHRA Pharma (Matshi 2013). Amazwe apho ellaOne yasungulwa ”. EParis: IHRA Pharma. Ishicilelwe kwasekuqaleni nge-28 kaJulayi 2013. Iphinde yafunyanwa nge-25 Matshi 2014.

ISIQINISEKISO NESIBONELELO:

Le nto ithengiselwe uKwenziwa koPhando kuphela. Imigaqo yokuthengisa Faka isicelo. Ayisetyenziselwa uBuntu, okanye oNyango, iZilwanyana, okanye abaNtu.


IAAA

HNMR

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