I-Raw Fasoracetam powder (110958-19-5) hplc =98% | AASraw Nootropics
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IFasoracetam powder

Akukho kalo SKU: 110958-19-5. Udidi:

I-AASraw ngumenzi oqeqeshiweyo we-Fasoracetam powder eluhlaza ene-lab ezimeleyo kunye nefektri enkulu njengenkxaso, yonke imveliso iya kwenziwa phantsi kolawulo lweCGMP kunye nenkqubo yokulawula umgangatho olandelwayo. Inkqubo yokubonelela izinzile, zombini ii-odolo zokuthengisa kunye ne-wholesale ziyamkeleka.Wamkelekile ukuba ulandele kwi-AASraw!

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1. Ividiyo yeFasoracetam Powder-AASraw

 


2. Iimpawu ezisisiseko zeFasoracetam Powder

igama: IFasoracetam powder
CAS: 110958-19-5
Ifomula yeMolekyuli: C14H27N3O2
Ubunzima Ezinto: 158.15
Melt Point: 160-166 ° C
Isitoreji sokugcina: Gcina kwiqondo lokushisa okanye upholile
umbala: Umpu omhlophe okanye omhlophe

 


3. Ingxelo yoVavanyo lwePowder eluhlaza yeFasoracetam-HNMR

IFasoracetam-110958-19-5-NMR-Spectrum

Yintoni i-HNMR kwaye ikuxelela ntoni i-spectrum ye-HNMR? H I-Nuclear Magnetic Resonance (NMR) ispectroscopy bubuchule bohlalutyo lwekhemistri esetyenziswa kulawulo lomgangatho kunye nophando lokufumanisa umxholo kunye nokusulungeka kwesampulu kunye nokwakheka kwemolekyuli. Umzekelo, i-NMR inokuhlalutya ngokobungakanani imixube equlathe iikhompawundi ezaziwayo. Kwiikhompawundi ezingaziwayo, i-NMR inokusetyenziselwa ukuthelekisa ngokuchasene neelayibrari ezibonwayo okanye ukuqikelela ulwakhiwo olusisiseko ngokuthe ngqo. Nje ukuba ulwakhiwo olusisiseko lwaziwe, i-NMR inokusetyenziselwa ukumisela ulungelelwaniso lwemolekyuli kwisisombululo kunye nokufunda iipropathi ezibonakalayo kwinqanaba lemolekyuli ezifana notshintshiselwano oluhambelanayo, utshintsho lwesigaba, ukunyibilika, kunye nokusasazwa.

4. Intoni ikunye neFasoracetam Umda?

I-Fasoracetam yi-nootropic yokwenziwa ye-racetams. Inkampani yaseJapan exuba amayeza ekuqaleni yayiphuhlisela ukunyanga isifo sengqondo esixhalabisayo semithambo, kodwa ukungabikho kokusebenza kakuhle kwaluphelisa uphuhliso lwayo olongezelelweyo.

Nangona kunjalo, isandula ukuvela kwakhona kulingo lwezonyango, kunye nophando olujonge amandla ayo okunyanga izifo zengqondo ezahlukeneyo kunye nokuphucula ukuqonda ngokubanzi.

Eli nyathelo lithatyathwe yi-Aevi Genomic Medicine eyaqala ulingo lwezonyango ukuphanda ukuba eli chiza linokubachaphazela njani abantu abakwi-autism spectrum disorder, abo banengxaki yokusilela kwingqalelo (ADHD), kunye nexhala.

5. I-Fasoracetam isebenza njani kwingqondo?

I-Fasoracetam isebenza ngokusebenzisana kunye nokulungelelanisa iinkqubo ezintathu ezibalulekileyo ze-neurochemical: i-glutamatergic, i-cholinergic, kunye ne-gabaergic systems.

Bobathathu banokusebenza kwisikhundla sokuphucula ukuqonda kunye neenzuzo ezinokubakho njengokuphuculwa komsebenzi wokuqonda, ukunciphisa inkungu yengqondo, kunye nokucaca okucacileyo kwengqondo.

Njengezinye izinto ze-nootropic, i-fasoracetam yokwandisa amanqanaba e-acetylcholine. Esi senzo se-cholinergic sinceda ukwandisa ukuqonda, inkumbulo, ukugxila, isimo sengqondo, ukuphaphama, i-neuroplasticity, kunye nememori yexesha elide.

Ngelo xesha, iphinda ivimbele ukuchithwa kwe-acetylcholine nge-cholinesterase, ikhuthaza ukufunyanwa kwayo ngama-receptors e-cholinergic.

Enye i-neurotransmitter esebenza kuyo yi-gamma-aminobutyric acid (GABA) ngokunyusa i-GABA (B) i-receptors.

Ama-receptors e-GABA akhoyo kuyo yonke inkqubo ye-nervous central kwaye, xa ivuliwe, ibangela ukunyanzeliswa kwe-excitation inhibition kwinkqubo ye-nervous central.

Ngamanye amagama, i-GABA ithambisa i-neurons ukukhuthaza ukuziva uzolile kunye nokwaneliseka. Ukongeza, ezi ndlela zinceda i-GABA ukoyisa ixhala, uloyiko, ukuphazamiseka kokulala, kunye nokudakumba.

Indlela yesithathu ibandakanya inkqubo ye-glutamate. I-Fasoracetam iphinda iguqule i-metabotropic glutamate receptors eziphambili, ezichaphazela imisebenzi yokuqonda, i-neuroprotection, i-synaptic plasticity, kunye nokukhathazeka ngokubanzi.

Ukungalingani kwe-neurotransmitter glutamate ukungalingani kunokudityaniswa nokuphazamiseka kwengqondo kunye nomzimba, kubandakanya uxinzelelo, i-ADHD, isifo sokuwa, kunye nesifo sika-Alzheimer, ukukhankanya ezimbalwa.

6. The Izibonelelo zeFasoracetam

  • Ngamana ungathuthukisa iMemori kunye noCognition jikelele

Kuvavanyo lwezilwanyana, i-fasoracetam ithintele ngokufanelekileyo okanye inciphise i-amnesia eyenziwe ngobuchule kunye nokulibala.

Nangona kungekho datha ifumaneka esidlangalaleni kuvavanyo olufanayo kwizifundo zabantu, abasebenzisi abaninzi bathi bafumana uphuculo olukhulu lwenkumbulo xa beyithatha.

Njengezinye i-racetam nootropics, i-fasoracetam yonyusa inani le-acetylcholine, i-neurotransmitter eyona nto inoxanduva lokukhumbula, ukufunda kunye nokuqonda.

  • Unokuxhoma ukuxhalabisa nokuxinezeleka

I-Fasoracetam inokuphucula isimo sengqondo, inciphise ukuxhalaba, kwaye iphakamise ukudakumba ngokusebenza kwiikhemikhali ezimbini ezinamandla kakhulu ezichaphazela ingqondo, i-glutamate kunye ne-gamma-aminobutyric acid (GABA).

Ngaxeshanye up-regulating GABA, eyi-neurotransmitter inhibitory, kunye nokucinezela ukuveliswa ngokugqithiseleyo kwe-glutamate ye-neurotransmitter ye-excitatory, i-fasoracetam inikezela oko abasebenzisi bachaza njengemvakalelo egudileyo, engeyiyo-jittery yokuphucula isimo sengqondo, ukuphumla kunye nokuzola.

Akukho zifundo ezifumaneka esidlangalaleni malunga nefuthe le-fasoracetam kwisimo sengqondo, ukuxhalaba, okanye ukuxinezeleka ebantwini, kodwa abasebenzisi abaninzi babika ukuba baziva bezolile, bexhalabile, kwaye benoxinzelelo oluncinci xa beyithatha.

  • I-ADHD Yonyango

Esinye sezifundo ezimbalwa ezikhoyo esidlangalaleni kwi-fasoracetam zibonisa ukuba inokuba lunyango olunokubakho lwe-ADHD.

Uphononongo, olubandakanya izifundo ze-30 phakathi kweminyaka eyi-12 kunye ne-17, luvavanye ukusebenza kwe-fasoracetam ekunyangeni i-ADHD phakathi kolutsha olubonise utshintsho oluthile kwinethiwekhi ye-glutamatergic gene. Olu tshintsho lunxulunyaniswa kakhulu ne-ADHD kwaye lukhona kwipesenti enkulu yolutsha olunengxaki.

Izifundo ezithatha i-fasoracetam kwiiveki ezintlanu zophononongo zibonise ukuphuculwa okuphawulekayo kuyo yonke imilinganiselo yeklinikhi ngexesha lovavanyo. Ukuncitshiswa kweempawu ze-ADHD kuqhubekile kuvavanyo lwasemva kovavanyo, kwaye akukho namnye kubathathi-nxaxheba kuphononongo obonise uphuhliso nokuba kukunyamezelana okanye ukuxhomekeka.

7. Fasoracetam isetyenziselwa ukuphucula umsebenzi wokuqonda

I-Fasoracetam ifunyenwe ingasebenzi kakuhle ukulwa nokukhubazeka kwememori ye-pathological ngenxa yeemeko ezinjenge-dementia okanye i-Alzheimer's Disease. Ngokuqhelekileyo, i-fasoracetam ibonakala ingasebenzi ekunciphiseni ukuncipha kwengqondo okunxulumene neminyaka kunye nokuphucula naluphi na uhlobo lwe-vascular-related cognitive impairment.

Oko kwathiwa, izifundo zezilwanyana zibonisa ukuba i-fasoracetam inokusebenza ngempumelelo ekukhuthazeni umsebenzi wememori. Kuphononongo olusele lukhankanyiwe - jonga ireferensi [1] - abaphandi bafumene ukuba ulawulo lwe-fasoracetam lukwazi ukuguqula ukukhubazeka kwememori okubangelwa yi-GABA receptor agonists. Olu phononongo lwenziwa kwiimpuku, kodwa indlela efanayo ikhona ebantwini; kunengqiqo ukuba ukunciphisa umsebenzi we-GABA receptor (okanye ukuguqula i-GABA receptors agnoists) kuya kuphucula umsebenzi wememori.

8. Kuphi ukuthenga Fasoracetam Umgubo?

Uphononongo lwethu lubonisa ukuba i-fasoracetam ibonisa isithembiso esikhulu sokulawula iingxaki ze-neurological ezifana neempawu ze-ADHD, i-autism spectrum disorder, kunye nexhala.

Ikwabonelela ngeenzuzo zokuphucula iindawo ezahlukeneyo zokuqonda ngokubanzi, njengokuphucula ukugxila kunye nokugxininiswa, ukunciphisa ukuphazamiseka kwememori, kunye nokuphucula ukukhumbula imemori, konke ngaphandle komngcipheko wokunyamezela okanye ukuxhomekeka. Oku kushwankathela yonke into ethembisayo ye-nootropics yokuphucula ukusebenza kwengqondo.

9. Isalathisi:

[1] "I-Fasoracetam kulutsha olune-ADHD kunye ne-glutamatergic gene network variants ephazamisa i-mGluR neurotransmitter signaling". ResearchGate. Ibuyiselwe ngo-2020-10-16.

[2] UMalykh, AG; Sadaie, MR (12 February 2010). "I-Piracetam kunye neziyobisi ezifana ne-piracetam: ukusuka kwisayensi esisiseko ukuya kwizicelo zeklinikhi ezinoveli kwiingxaki ze-CNS". Iziyobisi. 70 (3): 287–312.

[3] Tardner, P. “IFasoracetam njengonyango lwe-ADHD: Uphononongo olucwangcisiweyo lwedatha ekhoyo yeklinikhi• Ijenali yeHlabathi yeSayensi yokuSingqongileyo kunye neTekhnoloji. Ibuyiselwe ngo-2020-10-16.

[4] “Ushicilelo loMnxeba: i-Medgenics, Inc. Yazisa uTshintsho lwegama kwi-Aevi Genomic Medicine, Inc”. Aevi ngeMarketWired. Nge-16 kaDisemba 2016.

[5] Moskowitz, DH (2017). Ukufumana i-Genetic Cause kunye noNyango lwe-ADHD, i-Autism kunye ne-22q. BookBaby (ishicilelwe ngokwayo). ISBN 9781483590981.

10. Indlela yokuthenga Fasoracetam Umgubo ovela kwi-AASraw?

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