Thenga i-Levonorgestrel powder (797-63-7) hplc =98% | AASraw
I-AASraw ivelisa i-Cannabidiol (CBD) ipowder kunye ne-Hemp ebalulekileyo yeoyile ngobuninzi!

Levonorgestrel powder

I-AASraw ikunye kunye nokukwazi ukuvelisa kwigram ukuya kwi-masson ye-Levonorgestrel powder (i-797-63-7), phantsi komgaqo weCGMP kunye nolawulo lwekhwalithi ephezulu.

Levonorgestrel powder i-white crystalline powder yokwenziwa kwe-progestational hormone, isebenza ngokuthintela ukukhululwa kweqanda kwi-ovary okanye ukuthintela ukuchumisa kweqanda ngedoda (isetyhini zesalato zokuzala). Kwakhona kunokusebenza ngokuguqula umgca wesibeleko (isizalo) ukukhusela ukuphuhliswa kokukhulelwa. I-Levonorgestrel ngokuyinhloko isetyenziselwe ukuthintela ukukhulelwa, Idla ngokuxhomekeka kumxube we-racemic (Norgestrel, 6533-00-2).

Ingcaciso yeMveliso

 

Levonorgestrel powder ividiyo

 

 


 

Levonorgestrel powder Abalinganiswa basisiseko

 

 

igama: Levonorgestrel powder
CAS: 797-63-7
Ifomula yeMolekyuli: C21H28O2
Ubunzima Ezinto: 312.45
Iintetho: 13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one ;13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one ;13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1 ;17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one ;17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one ;17-ethynyl-18-methyl-19-nortestosteron ;17-ethynyl-18-methyl-19-nortestosterone ;18-methyl-17-alpha-ethynyl-19-nortestosterone
Melt Point: 206 ° C
Indawo yokubilisa: 459.1 ° C kwi-760 mmHg
Indawo yokuflasha: 195.4 ° C
Isitoreji sokugcina: 2-8 ° C
umbala: Powstalline powder

 


 

Iinkcukacha ezingakumbi. Ukugqithisa i-Levonorgestrel powder Ukwazi

 

igama

Levonorgestrel powder

 

Ukusetyenziswa kwe-Levonorgestrel kunye ne-dosing

I-1.
Kwizilwanyana eziphantsi, i-Levonorgestrel powder isetyenziswe kwi-monophasicand triphasiculations of combinations of contraceptive pills, kunye nezifo ezikhoyo ezivela kwi-100-250μg, kunye neendlela ezintathu ze-50μg / 75μg / 125μg. Idibene ne-estrogen ethinylestradiol kule mi qathango.
Kwi-dose yemihla ngemihla ephantsi kakhulu ye-30μg, i-Levonorgestrel powder isetyenziswe kwezinye iprogestogen kuphela ipilformulations.

 

Ukukhulelwa kwangokukhawuleza

I-powon Levonorgestrel isetyenziswe kwiipilisi zokukhusela ngokukhawuleza (ECPs), zombini kwi-regimen edibeneyo ye-Yuzpe equka i-estrogen, kwaye njengendlela ye-Levonorgestrel eyiluqu kuphela. Indlela ye-Levonorgestrel-powder kuphela isebenzisa i-Levonorgestrel i-powder eluhlaza i-1.5 mg (njengomlinganiselo omnye okanye i-0.75 mg imizuzu ye-12 iiyure ngaphandle) ezithatyathwe kwiintsuku ze-3 zesini esingakhuselekanga, kunye novavanyo olulodwa olubonisa ukuba liqala ngokukhawuleza njengeeyure ze-120 (iintsuku ze-5) emva kokulalana kunokusebenza.
Eyona ndlela iphambili yokusebenza kwe-Levonorgestrel powder eluhlaza njengepilisi ye-progestogen-kuphela yonyango lokuthintela ukukhulelwa, ngokwe-International Federation of Gynecology and Obstetrics (FIGO), ukuthintela ukuchumisa ngokuthintela i-ovulation kunye nokuqina kwencindi yomlomo wesibeleko. Ukuphononongwa kobungqina kuphakamisa ukuba i-LNG [levonorgestreol] ECPs ayinakuthintela ukumiliselwa kweqanda elichunyisiweyo. Ulwimi kumiliselo akufuneki lubandakanywe kwiileyibhile zemveliso ye-LNG ECP. ” Ngo-Novemba ngo-2013, i-Arhente yamaYeza yaseYurophu (i-EMA) yavuma utshintsho kwilebula isithi ayinako ukuthintela ukumiliselwa kweqanda elichunyisiweyo. Olunye uphononongo lisafumanisa ukuba ubungqina abukacaci. Ngelixa kungenakulindeleka ukuba ukuthintela inzala ngexesha likaxakeka kuchaphazele ukufakelwa akunakwenzeka ukuba ikhuphe ngokupheleleyo ukubakho kwesiphumo sasemva kokuchumisa. Ngo-Novemba ka-2013, i-EMA ikwavume ukutshintshwa kwelebheli ye-HRA Pharma's NorLevo isithi: “Kwizilingo zeklinikhi, ukusebenza ngokuthintela ukukhulelwa kuncitshisiwe kwabasetyhini abanobunzima obuyi-75 kg [i-165 yeepawundi] okanye nangaphezulu, kwaye i-Levonorgestrel powder yayingasebenzi kubantu basetyhini abanobunzima ngaphezulu kwe-80 kg. ”Ngo-Novemba ka-2013 nango-Janyuwari ka-2014, i-FDA kunye ne-EMA bathi bajonga ukuba ubunzima obonyukayo kunye nesalathiso sobunzima bomzimba (BMI) kunciphisa ukusebenza kweendlela zokuthintela ukungxamiseka.

 

Into ebalulekileyo ye-Levonorgestrel powder

  • Ukuphucula ubomi belolufu
  • Ukwakhiwa okuchanileyo
  • Ukucutshungulwa ngokwenyama
  • Ezinganyelwanga

 

Isilumkiso kwi-Levonorgestrel powder

I-Levonorgestrel ipowder eluhlaza iyafana nawo onke amayeza, ezinye iziphumo ezingafunekiyo zinokubakho ekusebenziseni i-Levonorgestrel powder. Njalo qhagamshelana nodokotela okanye oqeqeshiweyo wezempilo ngaphambi kokusebenzisa. Iziphumo eziqhelekileyo ezichaphazelekayo zokuthatha i-1.5 mg ye-Levonorgestrel powder eluhlaza kwizilingo zeklinikhi (ezichazwe yi-10% okanye ngaphezulu) zibandakanya: ukugabha, imihlathi, isiyezi, intloko ebuhlungu, isicaphucaphu, ukudakumba, amabala, ukuzuza ubunzima, ukwehlisa i-HDL, iintlungu zesisu, ukudumba kwebele emva kokukhonza, iintlungu zesibeleko,, ukulibaziseka kokuya exesheni, ukuya exesheni okunzima, ukopha kwesibeleko, kunye nokudinwa, amenorrhea. Ukungasebenzi kwesibindi kunye nezintso, ubunzima bebele baxhonywa .; iziphumo ebezingalindelekanga eziqhelekileyo (ezixelwe nge-1% ukuya kwi-10%) zibandakanya urhudo, ukugabha kunye nokuya esikhathini okubuhlungu; ezi ziphumo bezingalindelekanga zihlala zinyamalale ngaphakathi kweeyure ezingama-48, azinakho njengeepilisi zolawulo lokuzalwa eziqhelekileyo, ekufuneka zithathwe ngamanyathelo okuthintela ukukhulelwa amayeza alandelayo. Abasetyhini abatshayayo akufuneki bathathe (ngenxa yobunzima besifo sentliziyo).

 

I mi yalelo

I-Levonorgestrel powder (okanye i-norgestrel okanye i-D-norgestrel) isizukulwana sesizukulwana sesibini seprogestogen, singenasiphelo emanzini, sinqabile kwi-chloroform, i-ethanol kunye ne-methylene chloride. Ngenxa yokusebenza kwayo kweprogestogenic, i-Levonorgestrel ipowder eluhlaza ineempembelelo ze-antigonadotropic, kwaye iyakwazi ukunqanda ukuveliswa kwe-hormone yesini kunye ne-sex hormone kubasetyhini kunye namadoda, isenzo sokuthintela i-ovulation ngokukhupha i-gonadotrophin ukukhululwa kwi-pituitary gland. Oku kuphumela kumanqanaba athatywayo e-hormone evuselela i-hormone (FSH) kunye ne-hormone ye-luteinizing (LH) kunye nokuvinjelwa okulandelelweyo kokuphuhliswa kobugqwetha kunye ne-ovulation. Isetyenziswe njengesithako esisebenzayo kwezinye iiproductive ze-hormonal, ezibandakanya iipilisi zokukhulelwa komlomo, iprogestogen kuphela iipilisi, iipilisi zokukhusela eziphuthumayo, iinkqubo ze-intrauterine, izixhobo zokukhulelwa, kunye ne-hormone yonyango yokutshintshwa, kodwa ayikwazi ukukhusela kwizifo ezithathelwana ngesondo. kwaziwa ngokuba yiD- norethindrone, i-Kanok ketone ishiywe. Ukuba ufuna ukufumana iziphumo ezifanelekileyo, kufuneka uthathwe ngokukhawuleza kwangoko kwii-72 iiyure zokulala, kwaye okwesibini ii-12 iiyure kamva. Amachiza asebenza ngokukhawuleza emva kokuba athathwe emva kwesondo.

 

Levonorgestrel powder eluhlaza

I-10grams encinci.
Uphando malunga nobukhulu obuqhelekileyo (ngaphakathi kwe-1kg) lungathunyelwa kwiiyure ze-12 emva kokuhlawula.
Ukwenza umlinganiselo omkhulu (ngaphakathi kwe-1kg) ungathunyelwa kwimihla yokusebenza ye-3 emva kokuhlawula.

Levonorgestrelraw Ukukhishwa kwePowder

Ukubonelelwa kwikamva elizayo.

 


 

Indlela yokuthenga i-Levonorgestrel powder evela kwi-AASraw

 

1.Qhagamshelana nathi nge-imeyile yethu Inkqubo yokubuza, okanye i-skype ekwi-Intanethiummeli wenkonzo yamakhasimende (CSR).
2.Ukusibonelela ngobuninzi bakho kunye neadesi.
I-3.I-CSR yethu iya kukunika isingeniso, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuhambisa kunye nomhla wokufika oqikelelwayo (i-ETA).
I-4.Inkokhelo eyenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ze-12 (Ukuze ulandelwe ngaphakathi kwe-10kg).
5.Goods zifunyenwe kwaye zinike izimvo.