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IMedrogestone (977-79-7)

Akukho kalo SKU: 977-79-7. Udidi:

I-AASraw ine-synthesis kunye nobuchule bokuvelisa ukusuka kwigram ukuya kwi-oda ye-medrogestone (977-79-7), phantsi kommiselo we-CGMP kunye nenkqubo yolawulo lomgangatho olandelelweyo.

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Ingcaciso yeMveliso

Ividiyo yeMedrogestone (977-79-7) ividiyo


I-Medrogestone (977-79-7) Sukufunyanwa:

Ulwakhiwo lweKhemikhali: Igama lemveliso: IMedrogestone
Cas No.: 977-79-7
I-Molecular Formula: C23H32O2
Isisindo somzimba: 340.5
Iintetho: I-MEDROGESTONE

977-79-7

IMedrogesterone

IMetrogestone

Umda

Ukugcina: Emile, emnyama
Amaxwebhu (COA & HPLC njl.njl): iyafumaneka

I-Medrogestone (977-79-7) Dkubhala:

I-Medrogestone powder (INN), ekwabizwa ngokuba yi-6,17α-dimethyl-6-dehydroprogesterone, yiarhente yokuphuhlisa ethathwe kwi-17-methylprogesterone. Yabonakala njengenye indlela yokhetho olusebenzayo ngomlomo. osetyenzisiweyo kunyango lokubuyisela endaweni yehomoni kwiimpawu zokuya esikhathini kunye nonyango lokuphazamiseka kwengqondo.

Kwaye i-Medrogestone powder, ethengiswa phantsi kwegama lomkhiqizo iColprone phakathi kwabanye, iyeza leprogestin elisetyenziswe kunyango lwe-menopausal hormone kunyango lokuphazamiseka kwengqondo. Ifumaneka iyodwa kwaye idityaniswa ne-estrogen. Uthathwa ngomlomo.

I-Medrogestone yiprogestin, okanye i-progestogen eyenziwe, kwaye ngenxa yoko i-agonist ye-progesterone receptor, ujoliso lwendalo yeprogestogen njengeprogesterone. Inobuthathaka be-antiandrogenic, glucocorticoid, kunye nomsebenzi wokuchasa izifo kunye nokungabikho kweminye imisebenzi ebalulekileyo yehormone. Ngenxa yomsebenzi wayo we-progestogenic, i-medrogestone ineziphumo ze-antigonadotropic.

Imbekiselo:

  • 1: Schindler AE. I-dydrogesterone kunye nezinye iiproinsin zesifo sebele esinebele: isiguquli. U-Arch Gynecol Obstet. Ngo-2011 Feb; 283 (2): 369-71. doi: 10.1007 / s00404-010-1456-7. Epub 2010 Aprili 11. Uphononongo. I-PubMed PMID: 20383772.
  • 2: IPasqualini JR. Umhlaza wamabele kunye nee-enzymes ze-steroid zokuthambisa: indima yeeprogestogens. Maturitas. Ngomhla wamashumi amabini anesithandathu ka-2009; doi: 65 / j.maturitas.1. Epub 17 Disemba 21. Uphononongo. I-PubMed PMID: 10.1016.
  • I-3: IPasqualini JR. I-estrogen sulfotransferases ebeleni kunye nakwiseli yomhlaza. Ann NY Acad Sci. I-2009 Feb; 1155: 88-98. doi: 10.1111 / j.1749-6632.2009.04113.x. Uphononongo. I-PubMed PMID: 19250196.
  • I-4: IPasqualini JR. Iiprogestins zokuya esikhathini ukuya kubafazi abasempilweni nabaguli abanomhlaza webele. Maturitas. I-2009 Aprili 20; 62 (4): 343-8. doi: 10.1016 / j.maturitas.2008.12.008. Uphononongo. I-PubMed PMID: 19179024.
  • I-5: IPasqualini JR. Iproinsins nomhlaza wamabele. IGynecol Endocrinol. 2007 Oct; 23 Suppl 1: 32-41. Uphononongo. I-PubMed PMID: 17943537.