Ingcaciso yeMveliso
1. Ividiyo ye-Noopept Powder-AASraw
2. Iimpawu eziSisiseko zeNoopept Powder ekrwada
| igama: | I-Noopept (GVS-111) ipowder |
| CAS: | 157115-85-0 |
| Ifomula yeMolekyuli: | C17H22N2O4 |
| Ubunzima Ezinto: | 318.37 |
| Melt Point: | 97-98 ° C |
| Isitoreji sokugcina: | Ifriji |
| umbala: | I-White okanye i-white powstalline powder |
Intoni is Noopept Umda?
I-Noopept yinto eyaziwayo yokuphucula ingqondo kuluntu lwe-nootropic. Indlela ecetywayo yezenzo ezisekelwe kwizifundo zangaphambili zibandakanya ukunyuka kwe-acetylcholine ukubonakaliswa, ukwandisa ukubonakaliswa kwe-BDNF kunye ne-NGF, ukukhusela kwi-glutamate toxicity, kunye nokwanda kwe-neurotransmission ye-inhibitory kwingqondo.
Kuluntu lwe-nootropic, i-Noopept iyisincedisi esithandwayo sokuphucula ukusebenza kwengqondo. Ukwandiswa kokubonakaliswa kwe-cholinergic, ukunyuka kwe-BDNF kunye ne-NGF yokubonakalisa, ukukhuselwa kwi-glutamate toxicity, kunye nokwanda kwe-neurotransmission ye-inhibitory kwingqondo zezinye zeendlela ezicetywayo zeziphumo ezisekelwe kuphando lwangaphambili.
Yintoni iNoopept ilungele?
I-Noopept iyingqayizivele ngenxa yamandla ayo kunye neendlela ezikhawulezayo zesenzo, kunye nenani leenzuzo zengqondo ezinokubonelela.
Akunakwenzeka kuphela ukuba ufezekise izibonelelo zengqondo kunye nempilo yengqondo kwiidosi eziphantsi, kodwa i-anti-anxiety and neuroprotective effects zixhaphake kakhulu nge-noopept kunezinye i-nootropics.
Ukuba ulwa nenkungu yengqondo, ukuxhalaba, ukudakumba, ukwenzakala kwengqondo, okanye ukuncipha kwengqondo okunxulumene neminyaka, i-noopept inokuba yinto nje.
The Iinzuzo zeNoopept
Ukusebenza kwengqondo
Into ephambili yeNoopept kukugcina ukusebenza kwengqondo yakho. Esi songezo sinokubizwa ngokuba sisiphuculi sengqondo esiphucula imemori kunye nokusebenza kokufunda. Ngokuqhelekileyo, iingcali zincoma ukuthatha i-Noopept ngaphambi nje kwemisebenzi enzima ngengqondo ngenxa yezizathu ezininzi: sele sikhankanye eyokuqala, eyenzeka ngokukhawuleza; eyesibini kukuqinisa inkumbulo; kwaye eyesithathu yonyusa ingqalelo. Ngoko ke into eyenziwa nguNoopept ayikona nje ukunyuka kokugxila, ikwanceda ekuhlanganiseni onke amandla akho engqondo xa uyifuna kakhulu.
I-Noopept inokusebenza njengesixhobo sokuthintela ukuhla kwengqondo. Abantu abanembali yosapho kunye nokukhubazeka kwengqondo okanye sele bejongene nokunjalo banokuzama ukubandakanya i-Noopept kwindlela yabo yemihla ngemihla (ngokuqinisekileyo kunye nemiyalelo yedosi echazwe ngokucacileyo). Nangona kunjalo, ukungabikho kwezifundo ezinzulu malunga ne-Noopept ayikwazi ukuqinisekisa umphumo onamandla.
Isifo se-Alzheimer
Nangona sikhankanye uphawu olubalulekileyo olunxulumene nokuncipha kwenkumbulo, kuyafuneka ukwahlula imeko ye-Alzheimer's. Oko kungenxa yeprotheyini ye-amyloid, ehlala ibangela ukuvela kwe-Alzheimer. Yintoni eyenziwa nguNoopept kukunciphisa amanqanaba e-amyloid, nto leyo inciphisa ithuba lokujongana ne-Alzheimer kamva ebomini.
Ukunciphisa ixhala
Olunye uphawu lwe-Noopept yokuncedisa yinkxaso yokuzinza kwengqondo yakho okanye ngamanye amagama, ukupheliswa kweemvakalelo ezixhalabileyo. I-Noopept isebenzisana nenxalenye yengqondo yethu ebizwa ngokuba yiHippocampus kwaye apho ivuselela isimilo esichasene nexhala. Ngaloo ndlela, i-Noopept isizalisa ngokuzola kunye nentuthuzelo.
Ezinye iziphumo zenzululwazi zibanga ukuba i-Noopept inempembelelo ephawulekayo kubantu abane-cerebral trauma kwaye inceda kunyango lokulimala kwengqondo. Oku kunokuba malunga nenqaku lokuqala - ukuphuculwa komsebenzi wokuqonda - kwaye okwesibini - ukusebenzisana neHippocampus.
Antioxidant
I-Noopept ineempawu ze-antioxidant ezinokusebenza ekunciphiseni ukudumba okanye ukuthintela ezinye iimeko zomhlaza. Njengoko sisazi, i-antioxidants ilwa neeradicals zamahhala kwaye ngaloo ndlela, yakha ikhaka kwiiseli ezikhusela umonakalo. Iimpawu ezichasene nokuvuvukala zombini ingqondo kunye nomzimba kuyo nayiphi na into engalindelekanga kunye nokuqinisekisa impilo yonke.
Noopept isetyenziselwa ukuphucula umsebenzi wokuqonda
I-Noopept inokuba luncedo ngenxa yezizathu ezahlukeneyo kwaye inokusebenza ekuphuculeni umsebenzi wokuqonda, inkumbulo, ukusebenza kunye nempilo yengqondo.
Idlula kwisithintelo segazi-ingqondo ngokukhawuleza kunye nedosi ephantsi, kwaye umphumo uvame ukuvakala ngokukhawuleza.
Ukusetyenziswa kwe-noopept kukhuselekile nje ukuba uthatha iidosi ezicetyiswayo. Kukwangcono ukuqala kancinci, nokuba uthatha siphi na isizathu.
I-Noopept inikezela ngezakhono ezingcono zokulwa nokuxhalaba kunye ne-neuroprotective kunezinye i-nootropics, njengepiracetam, enegalelo ekunyuseni kwayo ukuthandwa.
Kuphi ukuthenga Noopept Umgubo?
I-Noopept sisongezelelo sokwandisa ingqondo enamandla kakhulu. Inokukunceda ukukhulisa inkumbulo, ukulinganisela isimo sengqondo, kunye nokunyusa izinga lokukhula kwe-synaptic kwingqondo. Ekuqaleni yenzelwe ukuba isebenze njengoguqulelo olunamandla ngakumbi lwepiracetam, i-noopept ihlala enye yeyona nootropics eyaziwayo ekhoyo namhlanje.
Ingxelo yoVavanyo lwePowder eluhlaza ye-Noopept-HNMR
Yintoni i-HNMR kwaye Ikuxelela ntoni i-spectrum ye-HNMR?H I-Nuclear Magnetic Resonance (NMR) ispectroscopy bubuchule bokuhlalutya bekhemistri esetyenziswa kulawulo lomgangatho kunye nophando lokumisela umxholo kunye nokusulungeka kwesampulu kunye nobume bayo bemolekyuli. Umzekelo, i-NMR inokuhlalutya ngokobungakanani imixube equlathe iikhompawundi ezaziwayo. Kwiikhompawundi ezingaziwayo, i-NMR inokusetyenziselwa ukuthelekisa ngokuchasene neelayibrari ezibonwayo okanye ukuqikelela ulwakhiwo olusisiseko ngokuthe ngqo. Nje ukuba ulwakhiwo olusisiseko lwaziwe, i-NMR inokusetyenziselwa ukumisela ulungelelwaniso lwemolekyuli kwisisombululo kunye nokufunda iipropathi ezibonakalayo kwinqanaba lemolekyuli ezifana notshintshiselwano oluhambelanayo, utshintsho lwesigaba, ukunyibilika, kunye nokusasazwa.
Noopept(157115-85-0)-COA
Indlela yokuthenga Noopept Umgubo ovela kwi-AASraw?
❶Ukuqhagamshelana nathi ngenkqubo yethu yokubuza nge-imeyile, okanye usishiyele inombolo yakho ka-whatsapp, ummeli wethu wenkonzo yabathengi (CSR) uya kuqhagamshelana nawe kwiiyure ezili-12.
❷Ukusinika ubungakanani obubuziweyo kunye nedilesi.
❸I-CSR yethu iya kukubonelela ngekoteyishini, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuthunyelwa kunye nomhla wokufika oqikelelweyo (ETA).
❹Intlawulo yenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ezili-12.
❺Impahla efunyenweyo kwaye unike izimvo.
Umbhali weli nqaku:
UGqr Monique UHong uthweswe isidanga kwiKholeji yase-UK Imperial yaseLondon kwiFakhalthi yezoNyango
Umbhali wephepha leJenali yeNzululwazi:
1. Igor S. Povarov
I-Brain Science Institute, iZiko loPhando lwe-Neurology, i-105064 eMoscow, eRashiya
2. UHalil Düzova
IYunivesithi yaseInonu, iFaculty of Medicine, iSebe lePhysiology, iMalatya, eTurkey
3. UPraveen K. Srivastava
ISakhiwo seShri GH Patel Pharmacy, iFaculty of Pharmacy, IYunivesithi yaseMaharaja Sayajirao yaseBaroda, Fatehgunj, Vadodara 390 002, Gujarat, India
4. Xueen Jia
ISebe lezoNyango zeBiochemistry kunye neBiophysics, iYunivesithi yaseUmeå, SE-90187 Umeå, eSweden
Lo gqirha/ingcali yenzululwazi ayinakuvuma okanye ithethelele ukuthengwa, ukuthengiswa, okanye ukusetyenziswa kwale mveliso nangasiphi na isizathu. I-Aasraw ayinayo indibaniselwano okanye ubudlelwane, ichazwa okanye ngenye indlela, kunye nalo gqirha. Injongo yokucaphula lo gqirha kukuvuma, ukuvuma kunye nokuncoma uphando olupheleleyo kunye nomsebenzi wophuhliso owenziwe ngoososayensi abasebenza kule nto.
isingqiniso
[1] Suliman, NA, Mat Taib, CN, Mohd Moklas, MA, Adenan, MI, Hidayat Baharuldin, MT kunye noBasir, R. (2016). Ukuseka i-Nootropics yeNdalo: Ukuphuculwa kweMolekyuli yakutsha nje ethotywe yi-Natural Nootropic. Ubungqina obusekelwe kwiNgxaki eyongezelelweyo kunye neyoNyango olulolunye, [kwi-intanethi] 2016, iphe.1-12.
[2] Picciotto, Marina R., Higley, Michael J. kunye noMineur, uYann S. (2012). I-Acetylcholine njenge-Neuromodulator: I-Cholinergic Signaling Shapes System yeNervous System kunye nokuziphatha. Neuron, [kwi-intanethi] 76 (1), iphepha 116-129.
[3] Gudasheva, TA, Grigoriev, VV, Koliasnikova, KN, Zamoyski, VL kunye neSeredenin, SB (2016). I-Neuropeptide cycloprolylglycine i-endogenous positive modulator ye-AMPA receptors. I-Doklady Biochemistry kunye ne-Biophysics, [kwi-intanethi] 471 (1), iphe.387-389.
[4] Tejeda, GS, Esteban‐Ortega, GM, San Antonio, E., Vidaurre, Ó.G. kunye noDíaz-Guerra, M. (2019). Uthintelo lwe-excitotoxicity-induced process ye-BDNF receptor TrkB-FL ikhokelela ekukhuselweni kwe-stroke. I-EMBO Molecular Medicine, [kwi-intanethi] 11(7).
[5] Voronina TA;Guzevatykh LS;Trofimov SS (2021). [Uphononongo oluthelekisayo lweziphumo zokuziphatha zexesha elide ze-noopept kunye nepiracetam kwiigundane zamadoda amadala kunye neempuku zabasetyhini ngexesha lokubeleka]. Eksperimental'naia i klinicheskaia farmakologiia, [online] 68(2).
