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Pregabalin powder

Akukho kalo SKU: 148553-50-8. Udidi:

I-AASraw ine-synthesis kunye nobuchule bokuvelisa ukusuka kwigram ukuya kwi-oda ye-Pregabalin powder (148553-50-8), phantsi kommiselo we-CGMP kunye nenkqubo yokulawulwa komgangatho olandelelweyo.

Ingcaciso yeMveliso

Pregabalin powder ividiyo


I-Raw Pregabalin powder Abalinganiswa basisiseko

igama: Pregabalin powder
CAS: 148553-50-8
I-molecular Formula: C8H17NO2
Isisindo somzimba: 159.23
Melt Point: 194-196 ° C
Isitoreji sokugcina: Ukushisa kwamagumbi
umbala: I-White okanye i-White Crystal Powder


Ukusetyenziswa kweplastiki ye-Raw Pregabalin kumjikelezo we-steroids

Amagama

I-Pregabalin powder ngokuqhelekileyo ibizwa nguLyrica ngabanini bomzimba okanye abakwaGGL.

Ukusetyenziswa kwePregabalin powder

Ukuxhamla
I-Pregabalin powder iyakuncedo xa idibene nezinye ionyango, xa ezinye ezo zonyango aziyikulawula ukuhluthwa okuyingxenye. Ukusetyenziswa kwayo yedwa kusebenze ngaphaya kweminye imithi yokuthatha. Akucaci indlela ekuthelekiswa ngayo ne-gabapentin kule ndlela yokusetyenziswa.

Intlungu ye-neuropathic
I-European Federation ye-Neurological Societies incoma i-Pregabalin powder njenge-arhente yokuqala yokunyanga intlungu enxulumene ne-neuropathy ye-diabetes, i-neuralgia ye-post-herpetic ne-central neuropathic. Incinci inokufumana inzuzo eninzi, kwaye inani elikhulu lifumana inzuzo ephantsi. Ezinye izalathisi zokuqala, ezibandakanya i-gabapentin kunye ne-tricyclic antidepressants, zinikezwa ubunzima obulinganayo njengabasebenzi bokuqala, kwaye ngokungafani ne-Pregabalin powder, ziyafumaneka njengama-generics aphantsi.

I-Pregabalin powder ayikhuthazwa kwezinye iintlobo zentlungu e-neuropathic efana ne-trigeminal neuralgia kunye nokusetyenziswa kwayo kwintlungu echaphazeleka ngumhlaza. Akukho bu bungqina bokusetyenziswa kwayo ekuthinteleni i-migraines kunye ne-gabapentin ifumaneka ukuba ayiyisebenzise. Kuye kwahlolwa ukuthintela intlungu emva kokuhlinzwa, kodwa ukusetyenziswa kwayo kule njongo kuyimpikiswano.

I-Pregabalin powder ngokuqhelekileyo ayithathwa njengendlela ephumelelayo kunyango lweentlungu. Izilingo zihlola ukusetyenziswa kwe-Pregabalin powder ukwenzela unyango lweentlungu eziphambili emva kokuhlinzwa, akukho miphumo kumanqanaba eentlungu jikelele, kodwa abantu babefuna i-morphine encinci kwaye banemiphumo emibini echaphazelekayo ne-opioid. Kuye kwaxoxwa ngeendlela eziliqela zokuphucula intlungu.

Izixhala
I-World Federation ye-Biological Psychiatry icebisa i-Pregabalin powder njengenye yezinto ezinokuqala zonyango zokunyangwa kwengxaki yokuxhalabisa, kodwa ikhuthaza ezinye i-agents ezifana ne-SSRI njengonyango wokuqala wendlela yokwenza ingxaki yokunyanzeliswa kunye nokukhathazeka kwangemva kwesifo. Kubonakala ngathi kuneziphumo ezixhalabileyo ezifana ne-benzodiazepines ezinobungozi obuncinci bokuxhomekeka.

Imiphumo ye-Pregabalin powder ibonakala emva kwe-1 iveki yokusetyenziswa kwaye iyafana nokusebenza kakuhle kwi-lorazepam, alprazolam, kunye ne-venlafaxine, kodwa i-Pregabalin powder ibonise ukuphakama ngokuvelisa iziphumo ezihambelanayo zokwelapha iimpawu zokukhathazeka kwengqondo. Izilingo zangexesha elide zibonise ukuphumelela okuqhubekayo ngaphandle kokuphuhliswa kokunyamezela, kwaye, ngaphezu koko, ngokungafani ne-benzodiazepines, inegalelo elincedo kwiindawo zokulala kunye nokulala, ezibonakaliswe ukuphuculwa kokulala kwe-wave-wave. Ivelisa ukukhubazeka okunzulu kwengqondo kunye nokukhathazeka kwengqondo xa kuthelekiswa nezobisi; Kwakhona kunakho amandla aphantsi okuxhatshazwa nokuxhomekeka kwaye kunokukhethwa phezu kwe-benzodiazepines ngezi zizathu.

Indlela i-Pregabalin powder isebenza ngayo

Indlela ekusebenziseni ngayo i-Pregabalin powder ayiqondi kakuhle. Kucingelwa ukuba kusebenze ngokubophelela kumashaneli e-calcium atholakala kwiiseli zesisombululo kwingqondo kunye nasentanjeni yomgudu. Oku kunciphisa ukukhululwa kwee-neurotransmitter ezahlukahlukeneyo kulezi zisele ze-nerve.

I-neurotransmitters yimizimba yemvelo yemvelo egcinwe kwiiseli zesiswini. Bandakanyeka ekudluliseni imiyalezo phakathi kweeseli zesisindo. I-Pregabalin powder kucatshangelwa ukunciphisa ukukhululwa kwama-neurotransmitters ebizwa ngokuba yi-glutamate, i-noradrenaline kunye nempahla

I-Glutamate yi-neurotransmitter eyenziwa njenge-natural 'nerve-exciting' agent. Ikhutshwa xa iimpawu zombane zakhiwa kwiiseli zesisongela kwaye emva koko zivakalisa iiseli ezininzi zamathambo. Kucingelwa ukuba kudlala indima ephambili ekubanjeni ukuxhwala. Ukunciphisa ukukhululwa kwe-glutamate kwiiseli zesisongela kwingqondo kucingelwa ukuba kuncede ukuzinzisa umsebenzi wombane kwintliziyo kunye nokukhusela isisu.

I-Glutamate, i-P kunye ne-noradrenaline nayo ibandakanyeka ekudluliseni iintlungu zengqondo kwindlela yengqondo kunye nenkqubo yesantya. Njengoko i-Pregabalin powder iyanciphisa ukukhululwa kwala ma-neurotransmitters ingasetyenziselwa ukunyanga iintlungu zentlungu eyenzeka ngenxa yengozi yomonakalo, okanye ukuphazamiseka emsebenzini.
I-Pregabalin powder ingasetyenziselwa ukhathaza ingxaki yokuxhalabisa, kunye enye imeko esicinga ukuba ifake phakathi komsebenzi we glutamate, i-substance P ne-noradrenaline kwingqondo.