Pregabalin powder ividiyo

 

 

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Abalinganiswa abasisiseko

Igama lemveliso:	Pregabalin powder
Inombolo ye-CAS:	148553-50-8
I-molecular Formula:	C8H17NO2
Isisindo somzimba:	159.23
Melt Point:	194-196 ° C
umbala:	Umgubo omhlophe okanye omhlophe wekristale
Isitoreji sokugcina:	RT

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Pregabalin Powder Reviews

I-Pregabalin powder ngumgubo omhlophe osetyenziswa njengechiza elichasayo ukuxhuzula, ukwabizwa ngokuba sisithinteli sokuxhuzula. Isebenza ngokunciphisa impembelelo kwingqondo ebangela ukuxhuzula. I-Pregabalin powder nayo ichaphazela iikhemikhali kwingqondo ezithumela iimpawu zentlungu kwi-nervous system.

I-Pregabalin powder isetyenziselwa ukunyanga intlungu ebangelwa yi-fibromyalgia, okanye intlungu ye-nerve kubantu abanesifo sikashukela (i-diabetic neuropathy), i-herpes zoster (i-post-herpetic neuralgia), okanye ukulimala kwentambo yomgogodla.

I-Pregabalin powder iphinda isetyenziswe kunye namanye amayeza ukunyanga ukutshatyalaliswa kwenxalenye yabantu abadala kunye nabantwana ubuncinane ubuncinane benyanga ye-1. I-Pregabalin ipowder eluhlaza ingasetyenziselwa iinjongo ezingadweliswanga kwesi sikhokelo sonyango.

 

Pregabalin Mechanism of Action

I-Pregabalin sisiyobisi se-anticonvulsant esisetyenziselwa ukunyanga iimeko zentlungu ye-neuropathic kunye ne-fibromyalgia, kunye nokunyangwa kwe-seizures inxalenye yokuqala ngokudibanisa nezinye i-anticonvulsants.

Nangona indlela yokusebenza ayizange icaciswe ngokupheleleyo, izifundo ezibandakanya iziyobisi ezinxulumene nolwakhiwo zibonisa ukuba ukubopha i-presynaptic ye-pregabalin kwi-voltage-gated calcium channels ngundoqo kwi-antiseizure kunye nemiphumo ye-antinociceptive ebonwa kwiimodeli zezilwanyana.

Ngokubophelela i-presynaptically kwi-alpha2-delta subunit ye-voltage-gated calcium channels kwinkqubo ye-nervous central, i-pregabalin imodareyitha ukukhululwa kwee-neurotransmitters ezininzi eziphazamisayo ezibandakanya i-glutamate, i-substance-P, i-norepinephrine, kunye ne-calcitonin gene ehlobene ne-peptide. I-alpha2-delta subunit ukusuka ekurhwetyweni ukusuka kwi-dorsal root ganglia ukuya kwi-spinal dorsal horn, enokuthi ibe negalelo kwindlela yokusebenza. Nangona i-pregabalin iyinto ephuma kwi-inhibitory neurotransmitter gamma-aminobutyric acid (GABA), ayibopheleli ngokuthe ngqo kwi-GABA okanye kwi-benzodiazepine receptors.

 

Usetyenziso/usetyenziso yePregabalin

❶ Ukusebenza kwe-Pharmacological: I-Pregabalin yi-novelγ-aminobutyric acid (GABA) i-receptor agonist, inokuthintela iziteshi ze-calcium ezixhomekeke kwi-voltage ukunciphisa ukukhululwa kwe-neurotransmitter.

❷ Eyona kliniki yonyango lweentlungu ze-peripheral neuropathic kunye nenxalenye yonyango lwe-adjuvant ye-focal seizures.

❸ Unyango lwesifo sokuxhuzula ekuphuhliseni elona yeza lithembisayo kunyango lwechiza olungcono nolulula ngakumbi. Ingasetyenziselwa ukunyanga iintlungu kunye nokuxhalaba.

 

Iziphumo eziPhakamileyo zePregabalin

Njengamachiza amaninzi, iLyrica inokubangela iziphumo ezibi okanye ezimbi kakhulu. Olu ayiloluhlu olupheleleyo lweziphumo ebezingalindelekanga kwaye ezinye zinokwenzeka. Umboneleli wezempilo unokukucebisa ngeziphumo ebezingalindelekanga. Ukuba ufumana ezinye iziphumo, qhagamshelana nosokhemesti okanye umboneleli wezempilo.

 

Iziphumo eziPhakathi

Unokufumana iziphumo ebezingalindelekanga ngelixa uthatha i-pregabalin. Iziphumo ebezingalindelekanga eziqhelekileyo ze-pregabalin ziquka:

▪ isiyezi

▪ ukozela

▪ ukubhideka

▪ ukungaboni kakuhle

▪ ukungcangcazela

▪ ukungazinzi xa uhamba

▪ ukutyeba

▪ ukuqhinwa

▪ umlomo owomileyo.

 

Iziphumo ezibi kakhulu

Shayela umnikezeli wakho ngokukhawuleza ukuba unemiphumo emibi kakhulu. Tsalela umnxeba ku-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unengxakeko yonyango. Iziphumo ezibi kakhulu kunye neempawu zazo zinokubandakanya oku kulandelayo:

▪ Iingcinga zokuzibulala okanye ukuzama ukuzibulala: Iimpawu zisenokuquka ukuzama ukuzibulala, ukuxhalaba okanye ukudandatheka okutsha okanye okuya kuqatsela, ukungalali kakuhle, ukuphazamiseka, ukwenza izinto ngenxa yeminqweno eyingozi nokutshintsha ngendlela engaqhelekanga kwisimo sengqondo okanye ukuziphatha.

▪ Ukwaliwa kakhulu: Iimpawu zayo zisenokuquka ukuphefumla nzima, ukurhabaxa, ukudumba kolwimi, imilebe, umlomo okanye umqala.

▪ Iingxaki zentliziyo

▪ Iingxaki ezinzulu zokuphefumla

Ezinye iziphumo ebezingalindelekanga zinokubangcono ekuhambeni kwexesha, ngelixa ezinye ezifana nokuba nesiyezi kunye nokozela zinokuhlala logama uthatha iyeza.

 

Pregabalin Ukugcinwa

Abantu kufuneka bagcine eli liyeza kwindawo yokushisa elawulwayo, malunga ne-68 degrees ukuya kwi-77 degrees Fahrenheit.

Ukuba uhamba, hlala uphethe iyeza lakho kunye nawe kwaye ugcine ibhotile okanye ibhokisi ebhalwe ngugqirha kwi-bag yakho. Musa ukushiya eli yeza kwimoto yakho, ngakumbi kubanda kakhulu okanye kushushu.

 

Isikhokelo sokuthenga i-Pregabalin Powder ukusuka kwi-AASraw inyathelo ngesinyathelo

♦ Tyelela iwebhusayithi ye-AAS, khetha i-pregabalin powder oyifunayo, kwaye ushiye umnxibelelwano kunye nomyalezo kwi-AAS wbsite, emva koko ungenise, Iinkonzo zabaThengi be-AAS ziyakuphendula kwiiyure ze-12 emva kokuba ifumene umyalezo wakho, emva koko uthethe ngeenkcukacha.

♦ Thumela nje i-imeyile okanye uthumele imiyalezo kwi-whatsapp kubantu abasebenza kwi-AAS kwaye ubaxelele ukuba ufuna ukuthenga i-pregabalin powder kwi-aasraw, emva koko uthethe ngokucacileyo, malunga nokucoceka, ubuninzi, ukuThumela, idilesi, ukhethe intlawulo efanelekileyo, iimpahla zinokuba ithunyelwe kwiiyure ze-12 emva kwentlawulo, emva kwentlawulo, uya kufumana inombolo yokulandela umkhondo, kunye nenkonzo yabathengi ye-AAS iya kukugcina uhlaziywe ngexesha, emva koko kufuneka uhlale phantsi ngokukhululekile, ulinde ipasile yakho.

♦ I-AAS yayiyinkampani yase-china, Ukhuseleko, ukuba unomhlobo e-China, unokuvumela abahlobo bakho ukuba batyelele inkampani yabo, bathethe ngokweenkcukacha, kwaye bafumane iimpahla ozifunayo.

 

isingqiniso

[1] Dworkin RH, O'Connor AB, Backonja M, et al. Ulawulo lwe-Pharmacologic yeentlungu ze-neuropathic: iingcebiso ezisekelwe kubungqina. Iintlungu 2007;132:237-51.

[2] Finnerup NB, Jensen TS. Ukusetyenziswa kweklinikhi ye-pregabalin ekulawuleni intlungu ye-neuropathic ephakathi. Izifo ze-Neuropsychiatric kunye noNyango 2007; 3: 885-91.

[3] Kalso E, Aldington DJ, Moore RA. Iziyobisi zentlungu ye-neuropathic. BMJ 2013;347:f7339.

[4] Mannix, Liam (Disemba 18, 2018). “Esi siyobisi sithandwayo sinento yokwenza nokuba likhoboka nokuzibulala. Kutheni oogqirha besoloko beyiyalela?” Amaxesha eCanberra. Igcinwe ukusuka kweyoqobo ngoDisemba 18, 2018. Ifunyenwe ngoDisemba 18, 2018.

[5] Nangona, uJames W.; Willmore, James; UBrumback, uRoger A. (2009). Unyango oluPhezulu kwiSithuthwane. PMPH-USA. p. 302. ISBN 978-1-60795-004-2.

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