TB-500

Yintoni i-TB-500?

I-TB500, ekwaziwa njenge-Thymosin Beta-4, yi-peptide yokwenziwa ephuma kwiprotheyini yendalo ebizwa ngokuba yi-thymosin beta-4. Iqulathe ulandelelwano lwee-amino acids kwaye ibingumxholo wophando kunye noqikelelo malunga nezicelo zonyango ezinokubakho. .

I-Thymosin beta-4 iveliswa ngokwemvelo emzimbeni womntu kwaye idlala indima kwiinkqubo ezahlukeneyo zomzimba, kubandakanywa ukuphiliswa kwenxeba, ukulungiswa kwezicubu, kunye nokulawulwa kokuvuvukala. ukwenzakala kwezicubu.

I-TB500, i-synthetic version ye-thymosin beta-4, idla ngokusetyenziswa kwizicwangciso zovavanyo kwaye ifumene ukuthandwa kwiindawo zezemidlalo kunye nokwakhiwa komzimba ngenxa yokukwazi kwayo ukuphucula ukubuyiswa nokukhuthaza ukuphilisa.Amanye amabango abonisa ukuba i-TB500 inokunceda ukukhawuleza ukulungiswa kwezicubu, ukwandisa ukukhula kwezihlunu, ukuphucula ukuguquguquka, kunye nokunciphisa ukuvutha.

TB 500 ulwazi lwangasemva

Njengoko bekutshiwo ngaphambili, i-TB-500 yinguqulelo eyenziweyo ye-Thymosin Beta 4, iprotein peptide eyenzeka ngokwemvelo kwimizimba yezilwanyana kunye nabantu. ulingo lwezonyango kusetyenziswa i-TB-500 kumahashe.

Uphando lwe-Thymosin kumahashe lwaqala ngo-1960. UDkt Allan Goldstein wenza i-thymosin alpha 1 ukunyusa umsebenzi we-immune cell cell kunye ne-thymosin beta 4 okanye i-TB-500 ukukhawulezisa ukuphilisa kunye nokulungiswa kwenxeba.

Ekuqaleni kweminyaka yoo-2010, i-synthetic version i-TB-500 kwakuvakala ukuba isetyenziswa kakhulu kumdyarho wamahashe. ukhuphiswano oluchasene namanye amahashe.lt ngeli xesha apho amanyathelo okuvavanya ukufumanisa i-TB-500 kumahashe omdyarho aqala ukuphuhliswa ngokunyanisekileyo.

I-TB-500, i-Thymosin beta-4, kunye nazo zonke ezinye izinto eziphuma apho ngoku zivaliwe kukhuphiswano lwamahashe, kunye nalo lonke ukhuphiswano lwezemidlalo oluphantsi kweKhowudi ye-Arhente yeHlabathi yokuLwa ukuDoping (WADA).

I-Thymosin yaqala ukusetyenziswa ebantwini ngo-1974, xa intombazana encinci ene-thymus gland engasebenziyo yafumana inaliti ye-substance. ,kwaye kwakhawuleza ukuchacha.

Isebenza njani i-TB-500 (i-Thymosin Beta-4)?

Indlela eyiyo yokusebenza ye-TB500 (i-Thymosin Beta-4) ayiqondwa ngokupheleleyo, kwaye uphando lokuseka iziphumo zalo ezichanekileyo emzimbeni luyaqhubeka.Nangona kunjalo, ngokusekelwe kulwazi olukhoyo, Nazi ezinye izicelo ezinokwenzeka ze-TB500:

Ukukhuthazwa kokufuduka kweeseli

I-TB500 icingelwa ukuba iphucule ukufuduka kweeseli, yinkqubo apho iiseli zifudukela kwindawo yokulimala okanye umonakalo. , ukuququzelela ukuphilisa kunye nokuvuselelwa kwezicubu.

Ukuguqulwa kokuvuvukala

Ngokumodareyitha isizukulwana kunye nomsebenzi wamamolekyuli avuthayo, i-TB500 inokuba nemiphumo echasayo.I-TB500 iboniswe ukunciphisa ukukhululwa kwe-cytokines e-pro-inflammatory, eyimichiza enendima ekuphenduleni okuvuthayo.TB500 inokunceda ukuseka ngakumbi indawo efanelekileyo yokuphilisa kunye nokulungiswa kwezicubu ngokunciphisa ukuvuvukala.

Ukuvuselela i-angiogenesis

I-Angiogenesis kukubunjwa kwemithambo yegazi emitsha.I-TB500 ibonakaliswe ukuba ikhulise i-angiogenesis, enokwenzeka ngokukhuthaza ukwanda kweeseli ze-endothelial kunye nokufuduka, okubalulekileyo ekudalweni kwemithambo yegazi. ukuvuselelwa kwezicubu.

Ukuveliswa kweCollagen

I-Collagen yiprotheni enika izicubu zenkxaso yesakhiwo.I-TB500 iye yacetywayo yokwandisa ukubunjwa kwe-collagen, enokunceda ekuhlaziyweni kwezicubu kunye nokuphulukiswa kwesilonda.I-TB500 inokunceda ukuqinisa kunye nokulungisa izicubu ezonakalisiweyo ngokunyusa i-collagen synthesis.

TB-500 inzuzo

I-TB-500 yinguqulelo eyenziweyo ye-peptide eyenzeka ngokwemvelo ekhoyo emzimbeni womntu.Ifumene ukuthandwa kuluntu lweembaleki kunye nolwakhiwo lomzimba ngenxa yeenzuzo zayo ezinokubakho. Nangona kubalulekile ukuqaphela ukuba uphando nge-TB-500 lusaqhuba, Nazi ezinye iingenelo ezinokuthi zicetyiswe:

Ukulungiswa kwezicubu kunye nokuvuselelwa

I-TB-500 icetyiswa ukuba ikhuthaze ukulungiswa kwezicubu kunye nokuvuselelwa.Inokukhuthaza ukukhula kwemithambo yegazi emitsha (i-angiogenesis) kwaye ikhuthaze ukubunjwa kwezicubu ezitsha, kubandakanywa izihlunu, i-tendon, i-ligaments, kunye nesikhumba. Oku kunokuba luncedo ngakumbi kubantu ukuchacha kukwenzakala, njengoko kunokukhawulezisa inkqubo yokuphilisa kunye nokuphucula impilo yezicubu.

Ukuphiliswa ngokukhawuleza kokwenzakala

I-TB-500 inokunceda ukukhawuleza ukuphulukiswa kweentlobo ezahlukeneyo zokulimala, ezifana ne-muscle strains, i-sprains, kunye neenyembezi ze-ligament.Kuye kwabikwa ukunciphisa ixesha lokubuyisela elifunekayo emva kokulimala ngokukhuthaza ukufuduka kwamaselula kunye nokusabalalisa kwindawo yokulimala. Oku kunokukhokelela ekuphulukiseni ngokukhawuleza kunye nokubuyela ngokukhawuleza kumsebenzi womzimba.

Ukuncitshiswa koKudumba

I-TB-500 ibonisa iimpawu ezichasayo, ezinokunceda ukunciphisa ukuvuvukala emzimbeni.Inokuthintela ukuveliswa kweemolekyuli ezivuthayo kunye nokukhuthaza ukukhululwa kwezinto ezichasayo, ngaloo ndlela kuncitshiswe ukuvuvukala kunye nentlungu ehambelana nayo. Abantu abaneemeko ezingapheliyo zokukrala njenge-arthritis, i-tendonitis, okanye i-bursitis.

Impilo yezicubu ezidibeneyo kunye nezidibeneyo

Ngokuxhasa ukulungiswa kwezicubu kunye nokunciphisa ukuvuvukala, i-TB-500 inokunceda ekuphuculeni i-joint and connective tissue health.Inokuphucula ingqibelelo kunye nokuqina kwee-tendon, iigaments, kunye ne-cartilage, ekhokelela ekuphuculeni umsebenzi odibeneyo, ukwandisa ukuguquguquka, kunye nokunciphisa umngcipheko wokulimala.

Ukukhula kwemisipha kunye nokuphucula

Nangona i-TB-500 ngokwayo ayiyona i-compounds yokwakhiwa kwemisipha ngokuthe ngqo, ingaba negalelo ngokungathanga ngqo ekukhuleni kwemisipha kunye nokubuyisela.Ngokukhuthaza ukulungiswa kwezicubu kunye nokunciphisa ukuvuvukala, kunokuxhasa inkqubo yokubuyisela emva kokuzivocavoca okukhulu okanye ukulimala.Oku kunokubangela ukukhawuleza kwemisipha. ukulungiswa kunye nokukhula, ukuphucula ukunyamezela kwemisipha, kunye nokunciphisa ubuhlungu bemisipha.

Ukuphucula izinwele

Kukho ubungqina obuthile obubonisa ukuba i-TB-500 inokuba nemiphumo emihle ekukhuleni kweenwele.Kukholelwa ukuba ikhuthaza ukukhula komthambo wegazi kunye nokuhanjiswa kwezondlo kwiifollicles zeenwele, ezinokuthi zikhuthaze ukukhula kweenwele kunye nobukhulu.Nangona kunjalo, uphando olongezelelweyo luyafuneka ukuseka le nzuzo ngokugqibeleleyo.

Impilo yeentliziyo

I-TB-500 ifundwe ngezibonelelo zayo ezinokuthi zibekho kwi-cardiovascular health.Inokukhuthaza ukukhula kwemithambo yegazi emitsha, iphucule ukuhamba kwegazi, kwaye iphucule umsebenzi wentliziyo. isifo se-artery.

Intoni iifomu ze-TB-500 ziyafumaneka?

Ifomu yePeptide engumgubo

I-TB500 umgubo ekrwada yinto ekrwada ukuvelisa umgubo we-lyophilized TB500 kwi-vial.Awulungele ukusetyenziswa ngabantu.Kuphando kuphela.

Umboniso

I-TB-500 (i-Thymosin Beta-4) ifumaneka ngohlobo lwe-lyophilized powder yokubuyisela kwakhona. Le powder yophilized idla ngokunikezelwa kwiibhotile okanye iikiti ze-vial. I-lyophilized powder ixutywe kunye ne-diluent efanelekileyo, njengamanzi e-bacteriostatic okanye oyinyumba. amanzi, ukwenza isisombululo sokutofa.

Kubalulekile ukuqaphela ukuba i-TB-500 yi-peptide yokwenziwa, kwaye ayifumaneki ngezinye iindlela ezinje ngeepilisi zomlomo okanye iikhrimu.Eyona ndlela yolawulo kukusebenzisa inaliti, i-intramuscularly, intravenously, okanye subcutaneous, njengoko kumiselwa lukhathalelo lwezempilo. yobuchwephesha.

Xa uthenga i-TB-500, kubalulekile ukuqinisekisa ukuba uyayifuna kumthengisi othembekileyo nothembekileyo ukuqinisekisa umgangatho kunye nokuthembeka kwemveliso.I-AASRAW ngumenzi we-peptide othembekileyo ukuthembela. ixabiso.

I-Peptide TB-500 isikhokelo sokusetyenziswa ngokutsha

TB500 ithamo

Ngenxa yokunqongophala kophando olupapashiweyo ukuza kuthi ga ngoku kwi-TB-500, akukho zincomo zedosi emiselweyo ngeenjongo zophando.

Nangona kunjalo, kwizifundo zesayensi kunye neklinikhi ukuza kuthi ga ngoku, uluhlu oluxhaphakileyo lwe-dosing ye-TB-500 luye lwaba yi-2-5 mg.TB-500 ngokuqhelekileyo ilawulwa nge-subcutaneous (phantsi kwesikhumba) okanye iinaliti ze-intramuscular, zilawulwa kabini ngeveki, Ubude bexesha le-4 ukuya kwiiveki ezi-8, kuxhomekeke kubume bophando. Abanye abezonyango bathanda idosi yokuqala ephezulu kwiveki e-1 ukuya kwezi-2, elandelwa yidosi yokulondoloza elingana nesiqingatha sedosi yokuqala kwiiveki ezi-2 ukuya kwezi-6 emva koko.

Isetyenziswa njani iTB-500?

Okokuqala, lungisa isisombululo se-TB-500 ngokuxuba ifom yomgubo we-lyophilized kunye namanzi e-bacteriostatic okanye amanzi angenazintsholongwane. Xa sele ixutywe, zoba umthamo ofanelekileyo kwaye uhlatywe kwindawo oyifunayo emva kokucoca indawo yokutofa nge-alcohol swab.

Abantu abaninzi bakhetha indlela ye-intramuscular ngokufaka inaliti kufuphi nendawo yokulimala, ngelixa indlela ye-intravenous ibandakanya ukufumana umthambo ochanekileyo wokujova.Okunye, indlela engaphantsi kwe-subcutaneous ibandakanya ukutyhala inaliti kwindawo yokulimala.

Emva kwenaliti, ukuphulula indawo ngobunono kunokukhuthaza ukuhanjiswa kwe-peptide okusebenzayo.Kubalulekile ukubonisana nengcali yezempilo ukuze ufumane isikhokelo somntu kwaye uqinisekise ukusetyenziswa okukhuselekileyo nokufanelekileyo kwe-TB-500.

Ukongeza, ukugcinwa okufanelekileyo kunye nokuphathwa kwepeptide kubalulekile ukugcina ukusebenza kwayo.

Idosi kunye nolwazi lolawulo olunikezelwe apha lwenzelwe iinjongo zolwazi kuphela kwaye akufanele luthathwe njengengcebiso yezonyango. Kuphela ligcisa lezempilo eliqeqeshiweyo linokubonelela ngesikhokelo esichanekileyo kunye nesomntu ngokusekwe kwiimeko zakho ezizodwa. Kubalulekile ukubeka phambili impilo kunye nokhuseleko lwakho ngokubonisana nochwepheshe bezempilo ngaphambi kokusebenzisa nawaphi na amayeza okanye unyango.

Ngubani ekufuneka asebenzise i-TB-500?

Unikezelo lwe-TB500 lukhulu.Kulula ukuyifumana kuba kukho ezininzi i-TB500 ezithengiswayo kwi-intanethi.Ukusetyenziswa kwe-TB-500 (i-Thymosin Beta-4) kufuneka kugqitywe kumntu ngamnye kwaye phantsi kwesikhokelo somsebenzi wezempilo. Isetyenziswa ngokuqhelekileyo kwiimeko ezilandelayo:

Iimbaleki kunye naBathanda ukomelela: I-peptide yophando ye-TB-500 ingasetyenziselwa iimbaleki kunye nabantu ababandakanyekayo kwimisebenzi enzima yomzimba ukuxhasa ukubuyiswa kwemisipha, ukukhuthaza ukulungiswa kwezicubu, kunye nokuphucula ukusebenza.

Ukubuyiswa kokulimala: Nabani na onobungozi obunxulumene nemisipha unokusebenzisa i-Tb-500.I-Peptide TB-500 isoloko isetyenziswa ngabantu abaphulukene nokulimala kwe-musculoskeletal, njenge-musculoskeletal strains, i-ligament iinyembezi, okanye i-tendonitis.Inokukunceda ukukhuthaza ukuphilisa, ukuvuselelwa kwezicubu kunye nokunciphisa. ukuvuvukala kwiindawo ezilimele.

Iimeko ezingapheliyo zokudumba: Abantu abaneemeko ezingapheliyo ezivuthayo ezifana nesifo samathambo, i-tendonitis, okanye i-bursitis banokuqwalasela ukusebenzisa i-TB-500 phantsi kolawulo lwezonyango.

Uncedo lweMpilo: I-TB-500 iphandwa ngokusetyenziswa kwayo kwiyeza elihlaziyiweyo.Inokuba neenzuzo ezinokubakho ekuphulukiseni isilonda, ukulungiswa kwezicubu, kunye ne-angiogenesis (ukukhula kwesitya segazi), okwenza kube yinto efanelekileyo kwiimeko ezahlukeneyo zonyango.

Ukhuseleko lwe-TB-500 kunye neziphumo ebezingalindelekanga

Nangona i-TB-500 ingakhange ifundwe ngokupheleleyo kukhuseleko lwabantu, iinkcukacha zangoku zibonisa ukuba ikhuselekile kwaye iyanyamezeleka xa ilawulwa ngokuchanekileyo.

• Ukukhathala
• intloko ebuhlungu
• I sizathu
• Utywala
• Umbono ogqabileyo
• Utshintsho kwisantya sentliziyo
• Ukugruzuka kwindawo yokutofa

Nangona kunjalo, ngenxa yokuba kukho ukunqongophala kolwazi malunga nokusetyenziswa kwexesha elifutshane okanye elide kwizifundo zabantu, abaphandi bayabongozwa ukuba baqaphele ngelixa besebenzisa i-TB-500.

• Utshintsho kuxinzelelo lwegazi
• Utshintsho lwesondlo
• Ubuhlungu kwisiza sokujola

Imiphumo emibi ngokuqhelekileyo iyancipha ngokwazo kwaye ihambelana nokusetyenziswa kweemveliso ze-peptide eziphantsi.Iimveliso ezinjalo, ezithengiweyo kubathengisi abangagunyaziswanga, zingabhalwa ngokungafanelekanga okanye ziqulethe izinto ezingcolileyo ezinobungozi.Ngelixa ininzi yomenzi we-peptide ethengisa iipeptide, sincoma umthengisi we-AASRAW.

Logama usenza yonke into ngokuchanekileyo ekusebenziseni i-TB-500 (ukusebenzisa ubuchule bokutofa obufanelekileyo,ukugcina ngokufanelekileyo kunye nokubuyisela i-peptide,ukubala idosi elungileyo,ukufumana i-TB-500 yodidi loxubo mayeza kuphela, njalo njalo.),akufane kwenzeke ukuba ungafane ucinge. jongana nezi ngxaki.

Kodwa ngenene iyenzeka – khumbula, ukungabikho kweziphumo ebezingalindelekanga ezimandundu kuphononongo lwezonyango olupapashiweyo ukuza kuthi ga ngoku akuthethi ngokuzenzekelayo ukuba aziyi kubakho xa usebenzisa i-TB-500.

Ungayithenga phi i-TB-500 kwi-intanethi?

Ungafumana abathengisi abaninzi be-TB-500 kwi-intanethi.Ezi webhusayithi zinokuthengisa ngokusemthethweni kuphela iipeptides ngeenjongo zophando.Ukuqinisekisa ukhuseleko lwe-TB-500, kucetyiswa ukuba zonke iipeptides zithengwe kubavelisi abahlangabezana nale migangatho ilandelayo yokuthembeka:

(1)Iipeptides kufuneka zonyulwe ngokungqongqo ukuba zisetyenziswe kwizicwangciso zophando.

(2) Umthengisi akafanele enze iziqinisekiso zonyango okanye amabango malunga neziphumo zolawulo lwepeptide.

(3) Iimveliso zePeptide kufuneka zize nezatifikethi ezisebenzayo zokuhlalutya (CoAs).

I-TB-500 Testing Report-HNMR

Yintoni i-HNMR kwaye Ikuxelela ntoni i-spectrum ye-HNMR?H I-Nuclear Magnetic Resonance (NMR) ispectroscopy bubuchule bokuhlalutya bekhemistri esetyenziswa kulawulo lomgangatho kunye nophando lokumisela umxholo kunye nokusulungeka kwesampulu kunye nobume bayo bemolekyuli. Umzekelo, i-NMR inokuhlalutya ngokobungakanani imixube equlathe iikhompawundi ezaziwayo. Kwiikhompawundi ezingaziwayo, i-NMR inokusetyenziselwa ukuthelekisa ngokuchasene neelayibrari ezibonwayo okanye ukuqikelela ulwakhiwo olusisiseko ngokuthe ngqo. Nje ukuba ulwakhiwo olusisiseko lwaziwe, i-NMR inokusetyenziselwa ukumisela ulungelelwaniso lwemolekyuli kwisisombululo kunye nokufunda iipropathi ezibonakalayo kwinqanaba lemolekyuli ezifana notshintshiselwano oluhambelanayo, utshintsho lwesigaba, ukunyibilika, kunye nokusasazwa.

Indlela yokuthenga i-TB-500 kwi-AASraw?

❶Ukuqhagamshelana nathi ngenkqubo yethu yokubuza nge-imeyile, okanye usishiyele inombolo yakho ka-whatsapp, ummeli wethu wenkonzo yabathengi (CSR) uya kuqhagamshelana nawe kwiiyure ezili-12.

❷Ukusinika ubungakanani obubuziweyo kunye nedilesi.

❸I-CSR yethu iya kukubonelela ngekoteyishini, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuthunyelwa kunye nomhla wokufika oqikelelweyo (ETA).

❹Intlawulo yenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ezili-12.

❺Impahla efunyenweyo kwaye unike izimvo.

Umbhali weli nqaku:
UGqr Monique UHong uthweswe isidanga kwiKholeji yase-UK Imperial yaseLondon kwiFakhalthi yezoNyango

Umbhali wephepha leJenali yeNzululwazi:
1. Ildiko Bock-Marquette
ISebe le-Biochemistry kunye neKhemistry yezoNyango, iYunivesithi yasePecs, iSikolo sezoNyango, iPecs H-7624, eHungary
2. UGabriel Sosne
ISebe le-Ophthalmology, i-Visual & Anatomical Sciences, i-Kresge Eye Institute, i-Wayne State University School of Medicine, e-USA
3. UOthman Othman
Isikolo seSayensi zoBomi, iCandelo lePhysiology, iPharmacology & Neuroscience, iYunivesithi yaseNottingham Medical School, iZiko lezoNyango laseQueens, eUnited Kingdom.
4. Harmanpreet Kaur
ISebe leKhemistry kunye ne-Biochemistry, iYunivesithi yaseWindsor, Windsor, Ontario, Canada
Lo gqirha/ingcali yenzululwazi ayinakuvuma okanye ithethelele ukuthengwa, ukuthengiswa, okanye ukusetyenziswa kwale mveliso nangasiphi na isizathu. I-Aasraw ayinayo indibaniselwano okanye ubudlelwane, ichazwa okanye ngenye indlela, kunye nalo gqirha. Injongo yokucaphula lo gqirha kukuvuma, ukuvuma kunye nokuncoma uphando olupheleleyo kunye nomsebenzi wophuhliso owenziwe ngoososayensi abasebenza kule nto.

Ucaphulo

[1] Ho EN, Kwok WH, Lau MY, Wong AS, Wan TS, Lam KK, Schiff PJ, Stewart BD.” Uhlalutyo lolawulo lwe-Doping lwe-TB-500, inguqulelo eyenziweyo yendawo esebenzayo ye-thymosin β₄, kumchamo we-equine kunye neplasma liquid chromatography-mass spectrometry.”J Chromatogr A. 2012 Nov 23;1265:57-69. doi: 10.1016/j.chroma.2012.09.043. Epub 2012 Sep 23.PMID: 23084823

[2] Esposito S, Deventer K, Goeman J, Van der Eycken J, Van Eenoo P.” Ukwenziwa kunye nokubonakaliswa kweqhekeza le-N-terminal acetylated 17-23 ye-thymosin beta 4 echongwe kwi-TB-500, imveliso ekurhaneleka ukuba inesakhono sokusebenzisa iziyobisi. ”Uvavanyo loMpondo weziyobisi. 2012 Sep;4(9):733-8. doi: 10.1002/dta.1402. Epub 2012 Sep 7.PMID: 22962027

[3] Imibhobho GT, Yang J.”Ukhuseleko lweCardio yiThymosin Beta 4.”Vitam Horm. 2016;102:209-26. doi: 10.1016/bs.vh.2016.04.004. Epub 2016 May 31.PMID: 27450736

[4] Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F Jr, Olson EN, Srivastava D.” I-Thymosin beta-4 ibonisa imikhomba-ndlela emitsha ekuphuhliseni amayeza okubuyisela ukuguga okuphumelelayo.”Int Immunopharmacol. 2023 Mar;116:109741. doi: 10.1016/j.intimp.2023.109741. Epub 2023 Jan 27.PMID: 36709593

[5] Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC. "Thymosin beta 4 regulation of actin in sepsis."Ingcali ye-Opin Biol Ther. 2018 Jul;18(sup1):193-197. doi: 10.1080/14712598.2018.1448381. Epub 2018 Mar 6.PMID: 29508629

[6] UJing J, uTian T, uWang Y, uXu X, uShan Y.” Uvavanyo oluninzi lweepeptides ezincinci ngealkaline esele isebenze ngaphambili kwisigaba esiqinileyo sokutsalwa kunye nolwelo lwechromatography-isisombululo esiphezulu sespectrometry kulawulo lwedoping. ”J Chromatogr A. 2022 Agasti 2; 1676: 463272. doi: 10.1016/j.chroma.2022.463272. Epub 2022 Jun 22.PMID: 35802965

---

Fumana ikowuti yoBuninzi