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I-Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2)

Akukho kalo
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi
SKU: 14605-22-2. Udidi:

I-AASraw ine-synthesis kunye nobuchule bokuvelisa ukusuka kwigram ukuya kwi-oda ye-Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2), phantsi kommiselo weCGMP kunye nenkqubo yolawulo lomgangatho olandelelweyo.

Ingcaciso yeMveliso

I-Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2) ividiyo


I-Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2) Sukufunyanwa:

Ulwakhiwo lweKhemikhali: Igama lemveliso: I-Tauroursodeoxycholic acid (TUDCA)
Cas No.: 14605-22-2
I-Molecular Formula: C26H45NO6S
Isisindo somzimba: 499.7
Iintetho:I-Tauroursodeoxycholic acid, TUDCA, Tauroursodeoxycholate, Taurolite
Ukugcina: Gcina i-20 ° C kude ukukhanya nokufuma.
Amaxwebhu (COA & HPLC njl.njl): Iyafumaneka

I-Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2) Dkubhala:

Amayeza amaTshayina asebenzise i-bile yezilwanyana kangangeminyaka engamakhulu njengeyeza ukunyanga izifo “ezinobushushu”. Yayisetyenziselwa ukukhulula i-spasms, ukunciphisa umkhuhlane, kunye nokuphucula ukujonga okubonakalayo. IBile yenziwa ngokwemvelo ngokusebenzisa i-cholesterol, equka imijikelezo kubandakanya i-taurochenodeoxycholic acid, ursodeoxycholic acid, kunye ne-chenodeoxycholic acid.Ngoku, i-UDCA kunye ne-TUDCA zaqala ukwenziwa ngonyaka ka-1954 eJapan.

I-Tauroursodeoxycholic acid powder yi-bile acid taurine conjugate evela kwiursoodeoxycholic acid. Inendima njenge-metabolite yomntu, i-arhente yokuchasana nokuvuvukala, iarhente ye-neuroprotective, i-inhibitor ye-apoptosis, iarhente yentliziyo kunye ne-arhente yolondolozo lwethambo. Isuka kwi-ursodeoxycholic acid. Yeyona asidi edibeneyo ye tauroursodeoxycholate.

I-Tauroursodeoxycholic Acid (TUDCA) luncedo lwesibindi olungeniswe njengezongezelelo yiThemmoLife kwimveliso yabo iLiver Longer. Ijongeka njengesixhobo esihle sokuthintela i-cholestasis, omnye umngcipheko omkhulu kunye ne-17 yealkylated steroids. I-Tauroursodeoxycholic Acid (TUDCA) yi-ambiphilic bile acid. Yindlela ye-taurine ye-conjugate ye-ursodeoxycholic acid (UDCA). Abantu bafunyanwa benamanani e-TUDCA. Nangona kunjalo, iibhere ziqukethe inani elikhulu le-TUDCA kwi-bile yabo. I-TUDCA inciphisa iziphumo ze-apoptotic, inceda ngokusebenza kwentliziyo, isifo sikaHuntington, isifo sikaParkinson, kunye nokubetha. Kutshanje, i-TUDCA ifunyenwe ineempembelelo ezikhuselayo esweni, ngakumbi ngokubhekisele kwi-retinal degenerative disc.

Imbekiselo:

  • Oveson BC, Iwase T, uHackett SF, uLee SY, Usui S, Sedlak TW, Snyder SH, Campochiaro PA, Sung JU (2011). Imimandla ye-bile, bilirubin kunye ne-TUDCA, ikhusela kuxinzelelo lwe-oxidative-invent to retine deuction. J. Neurochem. I-116 (1): 144–153. doi: 10.1111 / j.1471-4159.2010.07092.x. PMC 4083853. PMID 21054389.
  • UDuan, WJ, Zhang, FK, Ou XJ, Zhang, T, Wang, XM, Wang, Y, Cui, Y, Zhao, XY, Jia, JD (2011). "[Iiprofayili zeklinikhi yesifo sokuqala esiyimpembelelo ye-biliary cirrhosis nge-suboptimal biochemical reaction to ursodeoxycholic acid]". UZhonghua Gan Zang Bing Za Zhi. 19 (2): 118-120. doi: 10.3760 / cma.j.issn.1007-3418.2011.02.011 (engasebenziyo 2019-08-20). PMID 21492515.
  • Woo SJ, Kim JH, Yu HG (2010). "I-Ursodeoxycholic acid kunye ne-tauroursodeoxycholic acid ziyayicinezela i-choroidal neovascularization kwimodeli yempatho ye-laser". J Ocul Pharmacol Ther. 26 (3): 223–229. doi: 10.1089 / jop.2010.0012. I-PMID 20565307.

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