Ingcaciso yeMveliso
Testosterone engaxhaswanga Ividiyo yePowder-AASraw
Testosterone ekrwada undecanoate Powder Basic Characters
| Igama lemveliso: | I-Testosterone engekho ipetroli |
| CAS: | 5949-44-0 |
| I-molecular Formula: | C30H48O3 |
| Isisindo somzimba: | 456.71 |
| Melt Point: | 59-61 ° C |
| I-Assay: | 98% min(HPLC) |
| Isitoreji sokugcina: | -20 ° C Ifreezer |
| umbala: | Powstalline powder |
Testosterone undecanoate Imbali kunye Overview
I-Testosterone undecanoate yi-steroid esebenza ixesha elide kunye ne-slow-release, isebenza njenge-prodrug ye-testosterone, ukuba ithathelwe ingqalelo njengendalo kunye ne-bioidentical form ye-testosterone, inokuphendula ngokukhula okuqhelekileyo kunye nokuphuhliswa kwamalungu esini sesini. Yayiphuhliswe ekuqaleni ukusetyenziswa kwezonyango ukunyanga i-testosterone ephantsi ngu-Schering AG, kwi-1954.Ivunywe yi-US Food and Drug Administration (FDA), ugqirha uya kunika njenge-Testosterone Replacement Therapy (TRT), okanye ezinye iimeko (ezifana ne: umhlaza wedlala lobudoda, ukuncipha komzimba, kunye nokungasebenzi kakuhle ngokwesondo). Njengoko i-testosterone yayo ifakwe kwi-ester ye-undecanoate kwiqela le-17-beta ye-hydroxyl, enokwahlukana okukhulu kuyo yonke enye i-oral anabolic steroids njengoko ingenayo i-methylation (i-C-17 alpha alkylation) kwi-carbon ye-17. Ngoko, i-testosterone undecanoate ayiphumeleli kwimiphumo emibi kwisibindi njenge-C-17 alpha alkylated compounds. Ngaphandle koko, amandla e-Testosterone undecanoate kunye nexesha elide lesenzo, inokungena emzimbeni nge-lymphatic system ngokusebenzisa iphecana le-GI, ifakwe lula emzimbeni, idla ngokuba ngamachiza onyango akhethwayo kumanqanaba asezantsi e-Testosterone.
Yintoni i-Testosterone undecanoate Powder?
I-Testosterone undecanoate yaqala ukuthengiswa kwaye isasazwa kwi-intanethi ngeenjongo zonyango ngumzi-mveliso wayo, umenzi, umthengisi, ubonakala ngokubonakalayo kuzo zombini iifom ze-injectable kunye nezomlomo phantsi kwegama le-brand "Andriol, Aveed, Understor kunye neNebido phakathi kwabanye kule marike, ebizwa ngokuba yi "testosterone". undecylate, test undecanoate, test u, TU, etc”.
I-Testosterone i-undecanoate powder yi-ester ende ye-testosterone esetyenziswa kakhulu ukuphatha amanqanaba aphantsi e-Testosterone kumadoda. Okwangoku, isetyenziswa ngokubanzi ngabadlali kunye nabakhi bomzimba ukunyusa ukusebenza komntu wonke. Ngenxa yobude bayo besiqingatha sobomi, i-testosterone undecanoate powder ayifuni ukulawulwa rhoqo. Ngenxa yoko, iziphumo zayo ezilungileyo zinokulibaziseka kakhulu kwaye zisenokungaqali ukuba luncedo de kube kufutshane nesiphelo somjikelezo oqhelekileyo we-steroid. Ingena ngokwenyani kuyo yonke imijikelo kunye nezicwangciso zokusebenza, inokuphucula izakhono zabo zokwakha umzimba kunye nomsebenzi wesondo ngokubanzi, kwaye inokubanceda bafumane izihlunu kwaye balahlekelwe ngamafutha omzimba. Ngenxa yokuqalisa kwayo ngokukhawuleza kwesenzo kunye nesiqingatha sobomi obude emzimbeni, i-testosterone undecanoate powder ithathwa njengeyona nto isebenzayo kunoko. testosterone cypionate kunye ne-testosterone enanthate. Xa kuthelekiswa nezi ezinye iintlobo ze testosterone, ixabiso nalo liyabiza kakhulu.
Uthini umphumo kaTestosterone undecanoate powder sebenza emzimbeni wakho
I-Testosterone i-undecanoate powder yi-fatty chain chain acid efakwe kakuhle emzimbeni ngokusebenzisa amathumbu amancinci, emva koko i-metabolized kwisibindi ukuguqula i-testosterone. Xa le testosterone ingena egazini, iya kuyinamathisela kwi-androgen receptors, efumaneka kwiiseli ze-muscle. Emva kokuba i-testosterone ibophelela kula ma-receptors, ivuselela i-protein synthesis kunye nokukhula kwemisipha. I-Testosterone i-undecanoate powder yi-steroid esebenza ngokukhawuleza njenge-half-life-long-long, idinga ixesha elide ukugcina izinga elifanelekileyo lokuhlala kwinkqubo, ngoko inokulawula ukukhululwa kwehomoni emzimbeni. Ngoko ke, abaninzi abakhi bomzimba kunye nabadlali bathenga i-Testosterone undecanoate powder ukuphucula imbonakalo yabo yomzimba kunye namandla onke.
Kusetyenziswa kwanjani I-Testosterone engekho ipetroli Eyokwakha umzimba
(1)I-Testosterone engekho ipetroli umyinge
Ngaphambi kokuba uqale ukusebenzisa i-testosterone undecanoate powder, kubalulekile ukuchonga idosi efanelekileyo kunye nomjikelezo. I-Testosterone undecanoate powder dosage iyahluka ngokuxhomekeke kumntu kunye neenjongo zabo. Umlinganiselo oqhelekileyo uphakathi kwe-80 mg kunye ne-160 mg ngosuku; qala ngedosi ephantsi kwaye ngokuthe chu ulinyuse ukuze ufumane elona thamo lifanelekileyo; phinda lo mjikelo rhoqo kwiiveki ezi-4-6; kwaye uthabathe kunye okanye ngaphandle kokutya ngexesha elifanayo yonke imihla.
(2)I-Testosterone engekho ipetroli ubude bomjikelezo
I-Testosterone i-undecanoate powder ayiyona imveliso ye-testosterone ethandwa kakhulu, kufuneka isetyenziswe kumazinga aphezulu kubakhi bomzimba kunye nabadlali bezemidlalo ukuze bafumane ukusebenza okanye ukuphuculwa komzimba kumjikelezo wedwa ngenxa ye-bioavailability ephantsi. Desipe ukuba, iziphumo ze-testosterone undecanoate powder cycle zokwakhiwa komzimba ngokuqhelekileyo zivakalelwa ukuba zigcinwe kakuhle kunye nezinye i-anabolic steroids (ezifana ne-winstrol, i-anavar okanye i-nandrolone) ubuninzi bemiphumo yomjikelezo wayo. Inokuhlala ixesha elide kune-avareji yomjikelo ngenxa yendalo yayo ecothayo, kodwa inokunceda ukufezekisa iinjongo zempilo ezifanelekileyo. Njengoko siyazi ukuba, i-testosterone undecanoate powder yindlela ezinzileyo ye testosterone engavelisi imiphumo yecala ye-estrogenic, ibonakaliswe ukuvelisa ubuninzi bemisipha kunye namandla kunokuba enonthate ye testosterone okanye testosterone cypionate.
(3)I-Testosterone engekho ipetroli ubomi obulicla
Ngokuxhomekeke kumjikelezo, isiqingatha sobomi be-Testosterone Undecanoate powder yi-3 kwiiyure ze-7.
(4)I-Testosterone engekho ipetroli iziphumo zokwakha umzimba
I-Testosterone undecanoate powder yi-ester esebenza ngokukhawuleza efuna umjikelezo omde ukuze ufumane iziphumo ezisebenzayo, ukuba ungathanda ukuthenga i-Testosterone undecanoate powder kwi-intanethi njengeyeza eliphucula ukusebenza, le steroid ngokuqinisekileyo inokuzisa inzuzo enkulu kubakhi bomzimba okanye umsebenzisi osebenzayo. , ezi ziquka:
Ukwanda kweMisa yeMisipha: I-Testosterone undecanoate powder iyi-hormone ephambili yokukhula kwemisipha, inokukhuthaza ukukhula okukhulu kwemisipha kunye nophuhliso ngokunyusa amanqanaba e testosterone.
Ukonyuka Amandla kunye Nokuqina: Thatha i-testosterone undecanoate powder njengesongezelelo sinokubona ukwanda okukhulu kwamandla kunye nokuqina. Oku kunokuba luncedo kwiimbaleki kunye nabakhi bomzimba abafuna ukwenza okusemandleni abo ixesha elide.
AmaNqanaba aNciphisiweyo aMafutha: I-Testosterone i-powder undecanoate inokunciphisa amanqanaba amanqatha, ukunceda ukunciphisa umzimba kunye nokufezekisa i-physique ephilileyo.
Amaxesha oBuyiselo aPhuculweyo: I-Testosterone undecanoate powder inokunceda iimbaleki kunye nabakhi bomzimba ukuba babuyele ngokukhawuleza ekusebenzeni okukhulu.
Ukunciphisa umngcipheko wokulimala: I-Testosterone undecanoate powder inokunciphisa umngcipheko wokulimala ngokuncedisa izihlunu ekulungiseni umonakalo ngokukhawuleza. Ngenxa yoko, iimbaleki azinakwenzeka ukuba zidinwe okanye zonzakele ngexesha lokuzilolonga.
Testosterone undecanoate Pisikhova Unyango lwasemva koMjikelo (PCT)
I-synthesis yendalo ye testosterone emzimbeni wakho iya kunyanzeliswa ngokusebenzisa i-testosterone undecanoate powder, ubungakanani bolu xinzelelo buya kuxhomekeka kwidosi yale powder kunye naziphi na ezinye izinto ezisetyenziselwa umjikelezo wakho. Ukukhula kwakhona kwamanqanaba e testosterone yendalo kunokuncediswa ngonyango lwe-post-cycle. Ukubuyisela umzimba wakho kwimeko yawo yesiqhelo ekupheleni komjikelo, iPCT ibalulekile. Ukwenza i-PCT, ungasebenzisa iintlobo ezahlukeneyo zezongezelelo ezifana Clomid, Nolvadex, kunye neHCG. Khetha enye okanye ezimbini kwezi oza kuzithatha iiveki ezine, emva koko unciphise umthamo kwiimfuno zakho.
Iindlela zayo ezizezinye kwi-Testosterone undecanoate Powder
I-Testosterone i-powder undecanoate inokuthi ifakwe kunye nenani lezinye iindlela zendalo ukufezekisa iinjongo ezithile zokwakha umzimba, oku kulandelayo zizinto eziqhelekileyo eziqhelekileyo:
Isitaki sobuninzi: Testosterone undecanoate, Dianabol, kunye neHGH
Ukusika isitaka: Testosterone undecanoate, Winstrol, kunye neClenbuterol
Isitaki samandla: Testosterone undecanoate, Trenbolone, kunye neDeca Durabolin
Isitaki sokunyamezela: Testosterone undecanoate, Anavar, kunye Creatine
Ukubuyisela kwakhona: Testosterone undecanoate, BCAAs, kunye neglutamine
Ngelixa uhlobo ngalunye lwe testosterone replacement therapy (TRT) lunenzuzo yalo kunye nemingcipheko, zonke zijolise ekunyuseni ngobuchule amanqanaba e testosterone ngelixa zinciphisa umngcipheko weziphumo ebezingalindelekanga kunye noxinzelelo lwegazi. Ngenxa yoko, kubalulekile ukuthetha nogqirha phambi kokuba uqalise naziphi na ezinye iindlela zendalo.
Yintoni i Testosterone engaxhaswanga Pisikhova imiphumela
I-Testosterone undecanoate ithathwa njengonyango olukhuselekileyo nolusebenzayo lwe-testosterone (TRT), kodwa abasebenzisi banokufumana imiphumo enokubakho xa bengayazi indlela yokuyisebenzisa okanye ukusetyenziswa kakubi kwe-testosterone undecanoate powder dosage kunye nomjikelezo, ezi ziquka:
▪ Ukudinwa
▪ Ukuphuthelwa
▪ Ukutshintshatshintsha kweemvakalelo
▪ Ukutyeba
▪ Yandisa Amaqhakuva
▪ Iintlungu kwindawo yokutofa
▪ Inkqayi (Ukuqhawuka kweenwele)
▪ Gynecomastia
▪ I-Hypogonadism
▪ Uxinzelelo lwegazi
▪ Ukonyuka kwenqanaba le-estradiol
▪ Iienzymes zesibindi eziphakamileyo
▪ Ihypertriglyceridemia
▪ Umngcipheko wokwenziwa kwe-virilization (abasebenzisi basetyhini)
▪ Iinwele zomzimba ziyakhula (abasebenzisa abafazi)
▪ Ilizwi elinzulu (abasebenzisi abangabasetyhini)
Olu luhlu lungentla naziphi na ezi zimpawu ozifumanayo, nceda uyeke ukusebenzisa i-testosterone undecanoate powder kuqala, njengoko uninzi lwale mpembelelo yecala yesikhashana, iya kuzisombulula ngokwazo. Nceda uxelele ugqirha wakho ngokukhawuleza ukuba uyaqhubeka ukufumana ezi mpawu okanye ukuba ziba mandundu ekuhambeni kwexesha.
Ngowuphi umthombo okhuselekileyo ukuthenga Testosterone engaxhaswanga Umgubo?
I-Testosterone Undecanoate powder ibonakaliswe ikhuselekile kwaye iyasebenza ekuphuculeni iziphumo zokwakha umzimba, inokunceda ukwandisa ubunzima bemisipha, amandla kunye nokunyamezela, ngelixa kunokunciphisa amafutha omzimba. Ngenye yezona zinto zidumileyo zokunyusa i-testosterone kwintsimi yokwakha umzimba, iimpendulo ezininzi ezintle zingabonwa kubakhi bomzimba abaye basebenzisa le steroid. Ukuba uceba ukuyala i-testosterone ecocekileyo i-undecanoate powder kwi-intanethi, iwebhusayithi ye-steroid ehloniphekileyo iya kuba yinto ekhethekileyo.
AASraw ngumvelisi oyingcali we testosterone undecanoate powder onelebhu ezimeleyo kunye nefektri enkulu njengenkxaso, yonke imveliso iya kwenziwa phantsi kolawulo lweCGMP kunye nenkqubo yokulawula umgangatho elandelekayo. Inkqubo yokubonelela izinzile, ukuthengiswa kwe-testosterone undecanoate bulk powder kunye ne-wholesale orders ziyamkeleka.
I-Testosterone eluhlaza ye-undecanoate yoVavanyo lwePowder Report-HNMR
Yintoni i-HNMR kwaye Ikuxelela ntoni i-spectrum ye-HNMR?H I-Nuclear Magnetic Resonance (NMR) ispectroscopy bubuchule bokuhlalutya bekhemistri esetyenziswa kulawulo lomgangatho kunye nophando lokumisela umxholo kunye nokusulungeka kwesampulu kunye nobume bayo bemolekyuli. Umzekelo, i-NMR inokuhlalutya ngokobungakanani imixube equlathe iikhompawundi ezaziwayo. Kwiikhompawundi ezingaziwayo, i-NMR inokusetyenziselwa ukuthelekisa ngokuchasene neelayibrari ezibonwayo okanye ukuqikelela ulwakhiwo olusisiseko ngokuthe ngqo. Nje ukuba ulwakhiwo olusisiseko lwaziwe, i-NMR inokusetyenziselwa ukumisela ulungelelwaniso lwemolekyuli kwisisombululo kunye nokufunda iipropathi ezibonakalayo kwinqanaba lemolekyuli ezifana notshintshiselwano oluhambelanayo, utshintsho lwesigaba, ukunyibilika, kunye nokusasazwa.
Testosterone Undecanate (5949-44-0)-COA
Testosterone Undecanate powder (5949-44-0) -COA
Indlela yokuthenga Testosterone engaxhaswanga Umgubo ovela kwi-AASraw?
❶Ukuqhagamshelana nathi ngenkqubo yethu yokubuza nge-imeyile, okanye usishiyele inombolo yakho ka-whatsapp, ummeli wethu wenkonzo yabathengi (CSR) uya kuqhagamshelana nawe kwiiyure ezili-12.
❷Ukusinika ubungakanani obubuziweyo kunye nedilesi.
❸I-CSR yethu iya kukubonelela ngekoteyishini, ixesha lokuhlawula, inombolo yokulandelela, iindlela zokuthunyelwa kunye nomhla wokufika oqikelelweyo (ETA).
❹Intlawulo yenziwe kwaye iimpahla ziya kuthunyelwa kwiiyure ezili-12.
❺Impahla efunyenweyo kwaye unike izimvo.
Umbhali weli nqaku:
UGqr Monique UHong uthweswe isidanga kwiKholeji yase-UK Imperial yaseLondon kwiFakhalthi yezoNyango
Umbhali wephepha leJenali yeNzululwazi:
1. Mathias Hallberg
I-laboratory yaseBeijer, iSebe le-Pharmaceutical Biosciences, i-Neuropharmacology kunye noPhando lwe-Addiction, iYunivesithi yase-Uppsala, i-SE-751 24, eSweden
2. UMarc Gittelman MD
ISebe le-Urology, iYunivesithi yaseNew York yeSikolo sezoNyango, eNew York, NY, eU.SA
3. UJeffrey D. Freid MD
ICandelo le-Urology, iSebe lezoTyando, iYunivesithi yase-Utah School of Medicine, iSixeko saseSalt Lake, e-UT, eU.SA.
4. UStefan M. Pasiakos
ICandelo leZondlo zoMkhosi, i-US Army Research Institute of Environmental Medicine, eNatick, MA, eU.SA
Lo gqirha/ingcali yenzululwazi ayinakuvuma okanye ithethelele ukuthengwa, ukuthengiswa, okanye ukusetyenziswa kwale mveliso nangasiphi na isizathu. I-Aasraw ayinayo indibaniselwano okanye ubudlelwane, ichazwa okanye ngenye indlela, kunye nalo gqirha. Injongo yokucaphula lo gqirha kukuvuma, ukuvuma kunye nokuncoma uphando olupheleleyo kunye nomsebenzi wophuhliso owenziwe ngoososayensi abasebenza kule nto.
isingqiniso
[1] Corona, G., Maseroli, E., & Maggi, M. (2014). Injectable testosterone undecanoate kunyango lwe-hypogonadism. Uluvo lweNgcali kwi-Pharmacotherapy, i-15 (13), i-1903-1926. doi: 10.1517/14656566.2014.944896.
[2] Köhn FM, Schill WB (Novemba 2003). "Ukwenziwa komlomo omtsha we-testosterone undecanoate". Ijenali yeHlabathi yeUrology. 21 (5): 311–315. doi:10.1007/s00345-003-0372-x. PMID 14579074.
[3] Testosterone Undecanoate-Schering AG. Amachiza kwi-R&D. 5 (6): 368–369. 2004. doi:10.2165/00126839-200405060-00012. PMID 15563244.
[4] Jacobeit JW, Gooren LJ, Schulte HM (Septemba 2007). "I-testosterone esebenza ixesha elide ye-intramuscular undecanoate kunyango lwabantu ababhinqileyo ukuya kwindoda". Ijenali yezoNyango lwezesondo. 4 (5): 1479–1484. doi:10.1111/j.1743-6109.2007.00556.x. PMID 17635694.
[5] Ong GS, Somerville CP, Jones TW, Walsh JP (2012). "I-Anaphylaxis ebangelwa yi-benzyl benzoate kulungiselelo lwe-depot testosterone undecanoate". IiNgxelo zeeNgxelo kuNyango. 2012: 384054. doi: 10.1155/2012/384054. PMC 3261473. PMID 22272209. 384054.
[6] Behre HM, Abshagen K, Oettel M, Hübler D, Nieschlag E (Meyi 1999). "Inaliti ye-Intramuscular ye-testosterone undecanoate yonyango lwe-hypogonadism yamadoda: izifundo zesigaba I". Ijenali yaseYurophu ye-Endocrinology. 140 (5): 414–419. CiteSeerX 10.1.1.503.1752. doi:10.1530/eje.0.1400414. PMID 10229906.
[7] Zeziphi iihomoni ezidla ngokusetyenziselwa ukubuyisela umva ngesondo kwintlanzi (iGunya)
